isovaleramide/seizures

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[Isovaleramide, an anticonvulsant molecule isolated from Valeriana pavonii].

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BACKGROUND Fractioning of an extract of Valeriana pavonii, a native species used in Colombian folk medicine as tranquilizer, led to the isolation and identification of isovaleramide, one of the active constituents responsible for its central nervous system activity as

New antiepileptic drugs that are second generation to existing antiepileptic drugs.

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In the last decade, 10 new antiepileptic drugs (AEDs) have been introduced that offer appreciable advantages in terms of their favourable pharmacokinetics, improved tolerability and lower potential for drug interactions. However, despite the large therapeutic range of old and new AEDs, approximately

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