isovaleric acid/neoplasms

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Factors influencing the development of sigmoid colon cancer. Bacteriologic and biochemical studies.

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BACKGROUND Cancer of the sigmoid colon is especially sensitive to environmental factors such as food. The authors have conducted a series of studies with food as the external environmental factor and intestinal microflora as the internal environment factor in relation to sigmoid colon

In vitro and in vivo antineoplastic activity of a novel bromopyrrole and its potential mechanism of action.

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OBJECTIVE Many bromopyrrole compounds have been reported to have in vitro antineoplastic activity. In a previous study, we isolated N-(4, 5-dibromo-pyrrole-2-carbonyl)-L-amino isovaleric acid methyl ester (B6) from marine sponges. Here, we investigated the in vitro and in vivo antineoplastic

[Experimental pharmacologic and morphologic study of new platinum complexes].

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Antineoplastic and toxic properties of two newly synthesized complexes of platinum (II)--with isovaleric acid and with cystine, were studied on mice with ascitic tumour of Ehrlich. The studies were compared with cis-diaminodichloroplatinum (II) (cisplatinum). Data were obtained for high

[An attempt to degradation of anticancer drug and odor in the medical environment by photocatalyst].

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Currently, there is a need to reduce the occupational exposure of health care workers to anticancer drugs. Environmental contamination by anticancer drugs and subsequent exposure of health care workers are associated with vaporization of anticancer drugs. Furthermore, carcinomatous unpleasant odor

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