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Cytotoxic Effects of Diterpenoid Alkaloids Against Human Cancer Cells.

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Diterpenoid alkaloids are isolated from plants of the genera Aconitum, Delphinium, and Garrya (Ranunculaceae) and classified according to their chemical structures as C₁₈-, C₁₉- or C₂₀-diterpenoid alkaloids. The extreme toxicity of certain

Evaluation of Aconitum diterpenoid alkaloids as antiproliferative agents.

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Little information has been reported on the antitumor effects of the diterpenoid alkaloid constituents of Aconitum plants, used in the herbal drug 'bushi'. This study was aimed at determining the antitumor activities of Aconitum C19-and C20-diterpenoid alkaloids and synthetic derivatives against

Cytotoxic diterpenoid alkaloid from Aconitum japonicum subsp. subcuneatum.

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We explored new cytotoxic C₁₉-diterpenoid alkaloid, lipojesaconitine (1), from rhizoma of Aconitum japonicum THUNB. subsp. subcuneatum (NAKAI) KADOTA. Two additional non-cytotoxic new C₁₉-diterpenoid alkaloids, 10-hydroxychasmanine (2) and 3-hydroxykaracoline (3), together with

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