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leucomycin/vomiting

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ArticlesClinical trialsPatents
2 results

Comparative study on effects of 14- and 16-membered macrolides on gastrointestinal motility in unanaesthetized dogs.

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Comparative studies on the effects of 14-membered and 16-membered macrolides on gastrointestinal motility were conducted in unanaesthetized dogs. Midecamycin acetate, a new 16-membered macrolide, and leucomycin, another 16-membered macrolide, did not disturb the gastrointestinal motility and no dogs

Gastrointestinal motor-stimulating activity of macrolide antibiotics and analysis of their side effects on the canine gut.

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For clarification of the nature of the side effects of macrolide antibiotics on the gastrointestinal tract, the motor-stimulating activity of these agents was studied in unanesthetized dogs. The results showed that erythromycin and oleandomycin, the 14-membered macrolides with two side chain sugars
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