lindera pipericarpa/breast neoplasms

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Methyl linderone suppresses TPA-stimulated IL-8 and MMP-9 expression via the ERK/STAT3 pathway in MCF-7 breast cancer cells.

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Methyl linderone (ML), a cyclo-pentenedione, was isolated from the fruit of Lindera erythrocarpa Makino (family Lauraceae). This plant has well-known anti-inflammatory effects; however, the anti-cancer effects of ML have not yet been reported. Thus, the present study investigated the effects

Isolinderalactone enhances the inhibition of SOCS3 on STAT3 activity by decreasing miR-30c in breast cancer.

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Development of an efficient treatment for triple-negative breast cancer is an urgent issues. Compounds from plant extracts are a potential source of novel cancer treatment. Isolinderalactone, a kind of sesquiterpenoids compound, was purified from the root of Lindera strychnifolia and Neolitsea

Kanakugiol, a compound isolated from Lindera erythrocarpa, promotes cell death by inducing mitotic catastrophe after cell cycle arrest.

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A novel compound named kanakugiol was recently isolated from Lindera erythrocarpa and showed free radical-scavenging and antifungal activities. However, the details of the anti-cancer effect of kanakugiol on breast cancer cells remain unclear. We investigated the effect of kanakugiol on the

1, 3, 6-Trihydroxy-7-methyl-9, 10-anthracenedione isolated from genus Lindera with anti-cancer activity.

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BACKGROUND Natural products inhibiting fatty acid synthase are potential therapeutic agents to treat cancer. OBJECTIVE To investigate the chemical constituents of the root tubers of Lindera aggregate and the stems of Linderanacusua, and to find natural inhibitors on the expression level on fatty

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