machado-joseph disease/hypoxia

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Combined spinal-epidural technique for vaginal hysterectomy in a patient with Machado-Joseph disease.

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OBJECTIVE Machado-Joseph disease is a form of progressive spino-cerebellar ataxia with both bulbar and peripheral neurological manifestations. To date, anesthesia for patients affected by this disease has not been described. General anesthesia may be problematic because of the risk of pulmonary

Diverse mechanisms of autophagy dysregulation and their therapeutic implications: does the shoe fit?

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In its third edition, the Vancouver Autophagy Symposium presented a platform for vibrant discussion on the differential roles of macroautophagy/autophagy in disease. This one-day symposium was held at the BC Cancer Research Centre in Vancouver, BC, bringing together experts in cell biology, protein

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