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methyl alcohol/dental caries

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Results of long-term experimental studies on the carcinogenicity of methyl alcohol and ethyl alcohol in rats.

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Methyl alcohol was administered in drinking water supplied ad libitum at doses of 20,000, 5,000, 500, or 0 ppm to groups of male and female Sprague-Dawley rats 8 weeks old at the start of the experiment. Animals were kept under observation until spontaneous death. Ethyl alcohol was administered by

Orogranulocyte peroxidase activity as a measure of inflammatory periodontal disease.

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Benzidine dihydrochloride in the presence of dimethylsulfoxide reacts with myeloperoxidase contained within the granules of polymorphonuclear leukocytes obtained from the oral cavity. A blue meriquinoid oxidation product is formed in the presence of hydrogen peroxide, which can be extracted from the
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