The present study evaluated the antihyperlipidemic activity of myricetin, myricetrin, the alcohol fraction (AF) and the ethyl acetate fraction (EF) obtained from the bark of Myrica rubra (MR) in high-fat and high-cholesterol (HFHC) induced hyperlipidemic C57BL/6j mice. Mice were treated with
As the methanol extract of Myrica bark inhibited the activity of lipase in isolated mouse plasma in vitro, the influence of the extract on this enzyme in the gastrointestinal tube was investigated after oral intake. The methanol extract depressed the elevation of blood triglyceride level in olive
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