n propanol/erythema

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Barrier damaging effects of n-propanol in occlusion-modified tandem repeated irritation test: modulation by exposure factors and atopic skin disease.

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Recent studies provide evidence for significant and previously underestimated barrier damaging effects of repeated exposure to 60% n-propanol in healthy skin in vivo.We aimed to investigate further the cumulative effects of a range of n-propanol

Barrier Function and Natural Moisturizing Factor Levels After Cumula-tive Exposure to Short-chain Aliphatic Alcohols and Detergents: Results of Occlusion-modified Tandem Repeated Irritation Test.

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Alcohol-based disinfectants and detergents are common workplace factors for irritant contact dermatitis (ICD). Though occlusion and water are relevant co-exposures, the tandem effects of occlusion and sequential exposure to alcohols and detergents have not been studied. We therefore investigated the

Dermal tolerance of Sterillium, a propanol-based hand rub.

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Alcohol-based hand rubs have been used for hygienic hand disinfection in hospitals for decades. In order to achieve good compliance with hand hygiene practices in the healthcare setting, dermal tolerance of a hand rub product is crucial. Sterillium, which is used in many European countries for

Specific barrier response profiles after experimentally induced skin irritation in vivo.

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BACKGROUND Recently, natural moisturizing factors (NMFs) and corneocyte surface topography were suggested as biomarkers for irritant dermatitis. OBJECTIVE To investigate how exposure to different irritants influences corneocyte surface topography, NMF levels and the barrier function of human skin in

Effect of different alcohols on stratum corneum kallikrein 5 and phospholipase A2 together with epidermal keratinocytes and skin irritation.

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OBJECTIVE The aim of this exploratory study was to investigate the effect of ethanol, isopropanol and n-propanol on stratum corneum (SC) enzymes and keratinocytes in vitro together with their effects on skin condition and function. METHODS Activities of kallikrein 5 (KLK5) and phospholipase A2

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