The major cytotoxic activity of crude extracts of Nectandra rigida Nees is due to dehydrodiisoeugenol,the sample isolated being slightly enriched in the dextrorotatory enantiomer. Galgravin and two new tetrahydrofuranoid lignans, nectandrin A and nectandrin B, were also isolated and characterized
Oral health influences general well-being and quality of life. Oral diseases can be debilitating and are a major heath concern worldwide. Medicinal plants have been used for thousands of years for treating human diseases. Considering the emergence of multi-drug resistant pathogens and financial
BACKGROUND
The antiproliferative effect of eleven neolignans, two lignans and one diterpene isolated from three Lauraceae plants, four benzofurans and two bicyclooctanes synthetic derivatives was evaluated in vitro on a set of five human cancer cells from solid tumors with a high incidence in
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