perillaketone/perilla

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Analogues of perillaketone as highly potent agonists of TRPA1 channel.

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Transient receptor potential (TRP) channels represent interesting molecular target structures involved in a number of different physiological and pathophysiological systems. In particular, TRPA1 channel is involved in nociception and in sensory perception of many pungent chemesthetic compounds,

cDNA isolation and functional expression of myrcene synthase from Perilla frutescens.

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cDNA cloning of a monoterpene synthase from Perilla frutescens whose steam-distilled oil contains 92.9% perillaketone, was performed by the PCR method using primers designed based on limonene synthase. The full-length nucleotide sequence of this cDNA consisted of 1978 bp including a 1827-bp

Perilla frutescens var. frutescens in northern Laos.

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Twenty-eight samples of mericarps of Perilla frutescens var. frutescens were collected through fieldwork performed in Phongsali and Xieng Khouang provinces in northern Laos. No perilla samples were collected from Savannakhet province in the south although more than 20 sites were investigated.

Bioconversion of essential oil components of Perilla frutescens by Saccharomyces cerevisiae.

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The essential oil of perilla (Perilla frutescens) contains volatile low molecular weight compounds such as monoterpenes and phenylpropenes. The composition of the essential oil is classified into about ten chemotypes. The biosynthesis of these constituents is strictly controlled genetically. Among

[Comparative analysis of volatile components of medicinal materials from Perilla frutescens].

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OBJECTIVE To analyze the differences of volatile components of medicinal materials from Perilla frutescens (Perillae Folium; Perillae Caulis; Perillae Fructus). METHODS The volatile components were identified by HSGC/MS. The relative percentage content of the components were determined by peak area

[Advances in research of volatile oil and its different chemotypes in leaves of Perilla frutescens].

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The volatile oil is the main component in the leaves of Perilla frutescens. According to the main types of monoterpenoids or aromatic compounds, it can be divided into different chemotypes and the main chemotypes of Chinese producing Perilla are PA type (mainly containing Perilla aldehyde and

An Intestinal Propulsion Promoting Substance from Perilla frutescens and Its Mechanism of Action.

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Perillaketone, a monoterpenoid component of the essential oil, was isolated from the leaf of PERILLA FRUTESCENS as an active principle of intestinal propulsion in mice. Pharmacological studies on the mechanism of action of this compound have suggested that the promotion of intestinal propulsion,

Determination of Final Steps in Biosyntheses of Essential Oil Components in Perilla frutescens.

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Biosynthetic pathways of the essential oil components in PERILLA FRUTESCENS were examined by tracer experiments using [ (14)C]-labeled sucrose on two chemotypes: perillaketone (PK) and phenylpropanoid (PP-EM) types. The results of the experiments indicated that perillaketone is not converted from

Geraniol synthases from perilla and their taxonomical significance.

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Geraniol synthases were isolated from five pure strains of Perilla citriodora and Perilla frutescens which vary in essential oil type, the main compounds of which were citral, elsholtziaketone, perillaketone, and perillene, respectively. This result supports the putative biosynthetic pathways of

[Research on effects of chemotype and components of Perilla frutescens leaf volatile oil I: different phenological periods].

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This experiment researched on three kinds of Perilla frutescens including the widespread PK, PA and rare PL chemotype. The Perilla samples were the mature leaves collected in nutrition, flowering and frutescence three different phenological periods, and at 7 am, 12 pm and 6 pm three day time. The

Preliminary analysis on essential oil composition of Perilla L. cultivated in Lithuania.

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This study represents the investigation of the essential oil of Perilla frutescens (L.) Britton, Perilla frutescens (L.) Britton var. crispa f. viridis, Perilla ocymoides L. var. bicolorlaciniata leaves collected at full flowering stage in August 2007, in Lithuania. As biogenesis and composition of

Genetic analysis of essential oil variants in Perilla frutescens.

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A new chemotype (C type) of Perilla frutescens (Labiatae) that accumulates trans-citral as a main component of the essential oil in the leaf was crossed with five other chemotypes containing perillaldehyde (PA), elsholtziaketone (EK), perillaketone (PK), perillene (PL), and phenylpropanoid (PP) as

Taste-guided identification of high potency TRPA1 agonists from Perilla frutescens.

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Perilla frutescens is a food plant widely used in Asian cuisine. This plant was investigated for its interesting taste and somatosensory properties. Perillaldehyde and perillaketone are among the components of the aromatic extracts from P. Frutescens. These compounds were shown here to activate the

Anti-inflammatory constituents from Perilla frutescens on lipopolysaccharide-stimulated RAW264.7 cells.

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Perilla frutescens (L.) Britt. (Lamiaceae) is a traditionally medicinal herb in East Asian countries to treat various diseases. In present study, the low-polarity constituents of the aerial parts of P. frutescens were investigated and their anti-inflammatory effect on lipopolysaccharide

[Perilla resources of China and essential oil chemotypes of Perilla leaves].

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This study, based on the findings for Perilla resources, aimed to describe the species, distribution, importance, features, utilization and status of quantitative Perilla resources in China. This not only helps people to know well about the existing resources and researching development, but also

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