primin/hypersensitivity

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Structure-activity relationships in allergic contact dermatitis (I). Studies on the influence of side-chain length with derivatives of primin.

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Primin (2-methoxy-6-pentyl-1,4-benzoquinone) is a naturally-occurring strong sensitizer from Primula obconica (Primulacease). To determine the effect of side-chain length on sensitizing potency, 15 analogues with linear side chains from C1 to C15 and 4 C6-analogues with branched side chains were

Allergic contact dermatitis: clinical features and profile of sensitizing allergens in Riyadh, Saudi Arabia.

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BACKGROUND No reports are available on allergic contact dermatitis in Saudi Arabia, although it seems to be a common skin problem. We attempted to explore certain clinical aspects in addition to the profile of sensitizing allergens in our area. As no standard panel for patch testing is available in

Primula obconica--is contact allergy on the decline?

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Primula obconica, a member of the Primulaceae family, was introduced to Britain from China in 1880. P. obconica cultivars, which are reputed to contain less primin, have been developed over the past number of years in an attempt to reduce the incidence of allergic contact dermatitis. Primin

[Polyvalent contact allergy in a florist].

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A female florist, who ran a flowershop from 1954 to 1966 had to quit her job because of her known contact allergy due to chrysanthemums and primrose. Though in the meantime 12 years had passed she suffered occasionally from redness of the pharynx and stomachache after ingestion of tea prepared from

Contact hypersensitivity to sesquiterpene lactones in Chyrsanthemum dermatitis.

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In six persons with contact allergy to chrysanthemum of florists, patch tests were performed with 25 sequiterpene lactones. Positive responses were observed to 15 lactones. The most frequently encountered positive responses were to alantolactone (positive in all cases) and to arbusculin A,

Primin in the European standard patch test series for 20 years.

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Primin was included in the European standard series (ESS) in 1984. In 2000, a primin-free variant of Primula obconica, the main source of contact allergy to primin, was introduced in the market. The aim of this study was to analyse the trends of primin allergy in 13 986 consecutively patch-tested

Primin sensitization in north-eastern Italy: a temporal trend from 1996 to 2012.

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BACKGROUND Primin is the main contact allergen found in the ornamental plant Primula obconica Hance. OBJECTIVE To analyse the temporal trend of sensitivity to primin in north-eastern Italy and to evaluate the associations with occupations in our geographical area. METHODS From 1996 to 2012, 24 052

[Diagnosis of dermatitis due to plants].

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Contact dermatitis from plants may occur by several mechanisms. It may arise as a result of simple irritation or by allergic mechanism; co-exposure to sunlight can evoke the phenomena of phototoxicity or photoallergy. Etiologic diagnosis require botanical, chemical and immunologic knowledges. Patch

European Standard Series patch test results from a contact dermatitis clinic in Israel during the 7-year period from 1998 to 2004.

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The results of a 7-year retrospective study (1998-2004) from patch testing with the European Standard Series (ESS) establishing the frequency of sensitization in a contact dermatitis clinic in Israel are presented. 23 allergens were patch tested on 2156 patients, 1462 females (67.8%) and 694 males

Patch testing with Indian standard series.

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Hundred patients (61 males, 39 females) suspected to have allergic contact dermatitis were patch tested with Indian standard series (ISS). Forty four showed one or more positive reactions. The frequent sensitizers observed were nickel sulphate--12 (15%), potassium dichromate--11 (13.75%), cobalt

Epidemiological survey of standard series patch test results and observations on day 2 and day 4 readings.

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Computer data on 4721 consecutive patients patch tested with an extended standard series were analysed for the frequency of allergic reactions to each substance. Particular attention was given to the negative first reading at day 2 (D2) which later became positive at day 4 (D4). A total of 4210

[Changes in the European baseline series from 1981 to 2011 in a French dermatology-allergology centre].

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BACKGROUND Periodically updated, the European baseline series (EBS), first introduced in France in 1980, is an indispensable tool for the exploration of contact allergy. The aim of our study was to describe the prevalence of contact sensitization in a French centre between 1981 and 2011 to determine

Routine testing for Primula obconica: is it useful in the United States?

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Allergic contact dermatitis to Primula obconica has long been established. It is considered a significant allergen in Europe and has been included in standard screening there. The allergen is much less common in the United States. The frequency of allergy to P obconica in the United States is

Patch Test Results of the European Baseline Series among 1309 Patients in Turkey between 2013 and 2019

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Background: Prevalences of sensitivity to contact allergens change over time as a result of variations in allergen exposure. Objectives: The aim of the study was to describe

Associations between baseline allergens and polysensitization.

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BACKGROUND Identification of patients at risk of developing polysensitization is not possible at present. An association between weak sensitizers and polysensitization has been hypothesized. OBJECTIVE To examine associations of 21 allergens in the European baseline series to

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