pruritus ani/capsaicin

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Topical capsaicin--a novel and effective treatment for idiopathic intractable pruritus ani: a randomised, placebo controlled, crossover study.

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OBJECTIVE Pruritus ani is a common and embarrassing proctological condition which can be very difficult to treat. We report the results of a double blind placebo controlled study of treatment with capsaicin. METHODS Firstly, a pilot open study was carried out on five patients to establish which of

Pruritus ani.

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BACKGROUND Pruritus ani is a common presenting problem in general practice, one that is particularly distressing to patients. However, there is little available research on which to base management OBJECTIVE This article discusses the causes and management of this distressing symptom based on

Capsaicin and menthol in the treatment of itch and pain: recently cloned receptors provide the key.

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Topical capsaicin is reported to be an effective treatment for idiopathic intractable pruritus ani. While both capsaicin and menthol application produce a transient perianal burning sensation, only capsaicin relieves itching. Classical observations on functional desensitisation of nociceptors by

The role of capsaicin in dermatology.

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Neurogenic pain and pruritus are the common chief complaints at dermatology office visits. Unfortunately, they are also notoriously difficult conditions to treat. Topical capsaicin used as a single therapy or as an adjuvant offers a low-risk option for patients who do not achieve control on other

Systematic review of topical capsaicin in the treatment of pruritus.

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OBJECTIVE To determine the efficacy of topical capsaicin in treating pruritus in any medical condition. METHODS Cochrane library, Medline, Embase, Cinahl and Amed, up to April 2008. No language restrictions. METHODS Randomized, controlled trials comparing topically applied capsaicin with placebo or

Pruritus ani.

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BACKGROUND Anal pruritus affects up to 5% of the population. It is often persistent and the constant urge to scratch the area can cause great distress. Although usually caused by a combination of irritants, particularly faecal soiling and dietary factors, it can be a symptom of serious dermatosis,

Evaluation and management of common anorectal conditions.

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The prevalence of benign anorectal conditions in the primary care setting is high, although evidence of effective therapy is often lacking. In addition to recognizing common benign anorectal disorders, physicians must maintain a high index of suspicion for inflammatory and malignant disorders.

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