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pyrenacantha klaineana/breast neoplasms
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3 results
Pro-apoptotic and anti-adhesive effects of four African plant extracts on the breast cancer cell line MCF-7.
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BACKGROUND
Jatropha curcas (JCP1), Pyrenacantha staudtii (PS), Picralima nitida (ZI) and Jatropha gossypifolia (JCP2) are plants used in the African folklore for the treatment of various cancers.
METHODS
This study investigated the in vitro anticancer effects of the ethanol extracts against human
Pyrenacantha volubilis Wight, (Icacinaceae) a rich source of camptothecine and its derivatives, from the Coromandel Coast forests of India.
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Camptothecine, a potent eukaryotic topoisomerase inhibitor, is an important anticancer compound. The global demand for this compound was estimated to be $1 billion in 2003 and is only further expected to increase. Partly to meet the expected increase in demand, in the recent past, several efforts
New plant sources of the anti-cancer alkaloid, camptothecine from the Icacinaceae taxa, India.
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In this study, the production of camptothecine and its derivatives, in thirteen species of the family Icacinaceae, namely, Apodytes dimidiata, Codiocarpus andamanicus, Gomphandra comosa, Gomphandra coriacea, Gomphandra polymorpha, Gomphandra tetrandra, Iodes cirrhosa, Iodes hookeriana, Miquelia
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