quillaja/polysaccharide

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Adjuvant activity of QS-21 for experimental E. coli 018 polysaccharide vaccines.

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Three types of experimental vaccines containing O-side-chain polysaccharide from the enterotoxigenic strain Escherichia coli 018 were evaluated. The immunogenicity of free O-polysaccharide (PS), a polysaccharide-diphtheria toxoid conjugate (PS-conj), and detoxified lipopolysaccharide (dLPS) was

A purified saponin acts as an adjuvant for a T-independent antigen.

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Three strains of mice were injected with a T-independent antigen, Escherichia coli 055:B5 polysaccharide (PS) combined with purified saponin, QS-21, isolated from Quillaja saponaria bank. PS was prepared by hydrolysis of lipopolysaccharide (LPS). Nine week old mice were injected intradermally with

QS-21: a water-soluble triterpene glycoside adjuvant.

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QS-21 is a purified immunological adjuvant derived from a natural source, the bark of the tree Quillaja saponaria. It is a water soluble triterpene glycoside with amphiphilic character that can be mixed with a soluble antigen in a fully soluble vaccine formulation or combined with emulsion or

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