scleredema adultorum/hypoxia

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Severe diabetic scleredema with extension to the extremities and effective treatment using prostaglandin E1.

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We report a 49-year-old woman with severe diabetic scleredema (DS). The patient had non-insulin-dependent diabetes mellitus (NIDDM) for 9 years and noticed thickened skin on her back 3 years previously. Her DS rapidly extended to her back and extremities with pain and immobility. Her symptoms of DS

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