siderosis/albumin

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The role of endocytic pathways in cellular uptake of plasma non-transferrin iron.

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BACKGROUND In transfusional siderosis, the iron binding capacity of plasma transferrin is often surpassed, with concomitant generation of non-transferrin-bound iron. Although implicated in tissue siderosis, non-transferrin-bound iron modes of cell ingress remain undefined, largely because of its

The serum hepcidin:ferritin ratio is a potential biomarker for cirrhosis.

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BACKGROUND Serum hepcidin concentration is potentially affected by inflammation and iron stores in chronic liver disease (CLD), but little is known about the relationship between hepcidin and the degree of hepatic fibrosis. We investigated the potential role of serum hepcidin as a biomarker of

A non-transferrin-bound serum iron in idiopathic hemochromatosis.

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The nature of iron in the serum of patients with idiopathic hemochromatosis has been studied utilizing an isotope labeling method and results have been compared with those from normal individuals and patients with other forms of liver disease. Between 2 and 4% of a tracer dose of 59Fe added to

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