A crude extract of Cassia absus L. produced a dose dependent decrease in systemic arterial blood pressure and heart rate in pentothal anaesthetized rats. Repeated injections of the same dose of the crude extract (CA) showed tachyphylaxis. The cardio-vascular actions were not modified by pretreatment
The leaves of Cassia tora Linn. (Family: Caesalpiniaceae) were soxhlet extracted with methanol. The spasmogenic effects of the extract were evaluated on guinea pig ileum, rabbit jejunum and mice intestinal transit. Antinociceptive activity of the extract was also evaluated in the mice. The LD(50)
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