stellera chamaejasme/phenolic

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[Studies on phenolic compounds from Stellera chamaejasme].

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OBJECTIVE To study the chemical constituents of the roots of Stellera chamaejasme. METHODS The chemical constituents were separated and purified by chromatographic method after solvent extraction and were identified by spectroscopic analysis. RESULTS Two phenolic compounds were obtained and

Neochamaejasmin A inhibits KV1.4 channel activity via direct binding to the pore.

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Stellera chamaejasme L. (Thymelaeaceae) is a toxic perennial herb and widespread in Mongolia and the northern parts of China. Previous studies have revealed that Neochamaejasmin A (NCA), one of the main active ingredients in the plant roots, has many bioactivities such as inhibiting the

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