In this study, the root powder of Stellera chamaejasme was extracted with chloroform. The crude extract thus obtained was chromatographed several times with silica gel columns and finally one pure natural product was obtained. This product was identified as 2-isopropyl-5-methylphenol (thymol), which
OBJECTIVE
To study the chemical constituents of the root of Stellera chamaejasme L.
METHODS
Various column chromatographies on silica gel and RP-18 were employed for isolation and purification. Structures of compounds were elucidated by spectral analysis.
RESULTS
Eight lignans and three biflavonoids
The root powder of Stellera chamaejasme was extracted with chloroform. The crude extract obtained was chromatographed with silica gel columns many times. One pure natural product was obtained. It was identified as 7-hydroxycoumarin. Laboratory bioassay showed that it had a good insecticidal activity
The root powder of Stellera chamaejasme was extracted with petroleum ether. The crude extract obtained was chromatographed repeatedly with silica gel columns. One pure natural product was obtained, which was identified as 5-isopropyl-2-methylphenol (carvacrol), separated for the first time from the
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