urocanic acid/atrophy

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Immunotoxic effects of cis-urocanic acid exposure in C57BL/6N and C3H/HeN mice.

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Exposure to ultraviolet radiation results in increased levels of intradermal cis-urocanic acid (cUCA) and alters cutaneous immunity by interfering with processing and presentation of antigen by Langerhans cells. Reports on effects of systemic immunotoxicity with 30 day cUCA exposure in laboratory

Photogeneration and quenching of reactive oxygen species by urocanic acid.

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Urocanic acid, UCA, is characterized by two electronic transitions in the UV-B (280-320 nm) which comprise its broad absorption spectrum and give rise to wavelength-dependent isomerization quantum yields. The absorption spectrum of UCA extends into the UV-A (320-400 nm). Given the UV-A component of

[Presence of histidine-degrading enzymes in mycobacteria and nocardia and reaction-kinetic studies on Mycobacterium smegmatis SN 2 (author's transl)].

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The occurrence of histidine degrading enzymes in whole cells of mycobacteria and nocardia was investigated. Out of 25 Mycobacterium strains, only M. smegmatis showed "histidase" activity, i.e. an uptake of histidine and a simultaneous release of ammonia. Consequently, the presence of "histidase" is

Prevention of spontaneous and cyclophosphamide-induced diabetes in non-obese diabetic (NOD) mice with oral 2-acetyl-4-tetrahydroxybutylimidazole (THI), a component of caramel colouring III.

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The effect of oral administration of THI, a compound present in ammonia caramel food colouring, was studied in spontaneous and induced murine diabetes mellitus. Continuous administration of THI at 400 ppm in drinking water reduced the prevalence of spontaneous diabetes in female NOD/Lt mice from 63%

The gut microbiota confers protection in the CNS against neurodegeneration induced by manganism.

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Among all types of pollution, heavy metals are considered the greatest threat to human health, and heavy metals are associated with an increased risk of cardiovascular disease, coronary heart disease and neurodegenerative disorders. Manganese (Mn) exposure is well reported to exert neurotoxicity and

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