The human cytochrome P450 2A6 (CYP2A6) and monoamine oxidases (MAO-A and MAO-B), catalyzing nicotine and dopamine metabolisms, respectively, are two therapeutic targets of nicotine dependence. Vernonia cinerea, a medicinal plant commonly used for treatment of diseases such as asthma and bronchitis,
BACKGROUND
Vernonia amygdalina Del. (VA) (Asteraceae) is commonly used to treat hypertension in Malaysia.
OBJECTIVE
This study investigates the vasorelaxant mechanism of VA ethanol extract (VAE) and analyzes its tri-step FTIR spectroscopy fingerprint.
METHODS
Dried VA leaves were extracted with
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