Efficacy and Safety of Fermented Ginseng Powder on Liver Function
Palabras clave
Abstracto
Descripción
The investigators performed a 12-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of fermented ginseng powder on improvement of Liver function. The investigators measured ALT(Alanine Transaminase) profiles, Liver function index, fatty liver grade, lipid metabolism index, total antioxidant capacity, imflammation index, and Multidimensional Fatigue Scale.
fechas
| Verificado por última vez: | 01/31/2018 |
| Primero enviado: | 03/22/2017 |
| Inscripción estimada enviada: | 08/20/2017 |
| Publicado por primera vez: | 08/23/2017 |
| Última actualización enviada: | 01/31/2018 |
| Última actualización publicada: | 02/04/2018 |
| Fecha de inicio real del estudio: | 06/30/2016 |
| Fecha estimada de finalización primaria: | 10/31/2016 |
| Fecha estimada de finalización del estudio: | 07/31/2017 |
Condición o enfermedad
Intervención / tratamiento
Dietary Supplement: fermented ginseng powder
Dietary Supplement: Placebo
Fase
Grupos de brazos
| Brazo | Intervención / tratamiento |
|---|---|
| Experimental: fermented ginseng powder tablets (2 tablets/day, 125 mg & 500 mg/day) for 12 weeks. | Dietary Supplement: fermented ginseng powder tablets (2 tablets/day, 125 mg & 500 mg/day) for 12 weeks. |
| Placebo Comparator: Placebo Placebo for 12 weeks. | Dietary Supplement: Placebo Placebo for 12 weeks. |
Criterio de elegibilidad
| Edades elegibles para estudiar | 19 Years A 19 Years |
| Sexos elegibles para estudiar | All |
| Acepta voluntarios saludables | si |
| Criterios | Inclusion Criteria: - Age 19-70 years with ALT 35-105 IU/L Exclusion Criteria: - Under antipsychotic drugs therapy within past 2 months - History of alcohol or substance abuse - Participation in any other clinical trials within past 2 months - Laboratory test by show the following results - Serum Creatinine > 2.0 mg/dl - Pregnancy or breast feeding etc. |
Salir
Medidas de resultado primarias
1. Changes of ALT(Alanine Transaminase) [Baseline and 12 weeks]
Medidas de resultado secundarias
1. Changes of Liver function index [Baseline and 12 weeks]
2. Changes of fatty liver grade [Baseline and 12 weeks]
3. Changes of lipid metabolism index [Baseline and 12 weeks]
4. Changes of total antioxidant capacity [Baseline and 12 weeks]
5. Changes of imflammation index [Baseline and 12 weeks]
6. Changes of Multidimensional Fatigue Scale [Baseline and 12 weeks]
