Potential Biomarkers for Early Diagnosis of Acute Aortic Dissection
Palabras clave
Abstracto
Descripción
This is a prospective clinical study designed to procure blood samples from patients who present to the Emergency Department with suspected AAD.
Subjects enrolled in this study will sign and informed consent and have 3 blood samples drawn at different time points during their emergency department visit. In addition, data will be collected about the patient's health history, hospital procedures, and final diagnosis.
Blood samples collected in this study will be sent to laboratory for long-term storage and analysis in the future for these blood markers as they become available. No genetic testing will be conducted on these samples.
fechas
Verificado por última vez: | 04/30/2013 |
Primero enviado: | 05/03/2013 |
Inscripción estimada enviada: | 05/21/2013 |
Publicado por primera vez: | 05/22/2013 |
Última actualización enviada: | 05/23/2013 |
Última actualización publicada: | 05/26/2013 |
Fecha de inicio real del estudio: | 04/30/2013 |
Fecha estimada de finalización primaria: | 01/31/2014 |
Fecha estimada de finalización del estudio: | 03/31/2014 |
Condición o enfermedad
Fase
Grupos de brazos
Brazo | Intervención / tratamiento |
---|---|
acute aortic dissectin patients definite diagnosis by computed tomography arteriography (CTA). | |
acute chest pain patients aortic dissection is exclude by aorta CTA |
Criterio de elegibilidad
Edades elegibles para estudiar | 18 Years A 18 Years |
Sexos elegibles para estudiar | All |
Método de muestreo | Non-Probability Sample |
Acepta voluntarios saludables | si |
Criterios | Inclusion Criteria: - chest pain without diagnosis confirmed - symptom occurred in 2 hours - ≥18 years old - Can complete the base information - Able and willing to give written consent Exclusion Criteria: - known AAD - known causes of acute chest pain such as tumour and trauma - pregnant or lactating female - Associated chronic inflammatory diseases |
Salir
Medidas de resultado primarias
1. Diagnostic accuracy(sensitivity and specificity of 400 participates for diagnosing acute aortic dissection) of serum biomarkers on patients with AAD. [1 day (Emergency room without follow-up)]