The Only Blood Culture for Diagnosis of Bacteremia - Comparative Study of Practice
Palabras clave
Abstracto
Descripción
Blood cultures will be collected from patients admitted with on of the following signs: fever (≥38.5°C), hypothermia (≤36°C), chills or shock. For the first blood culture, 40 mL of blood will be obtained aseptically by a single phlebotomy and equally distributed into two BacT/Alert FA aerobic bottles and two BacT/Alert FN anaerobic bottles (bioMérieux, La-Balme-les-Grottes, France). The four bottles will be labelled from one to four in the following order: aerobic-anaerobic-aerobic-anaerobic. Within the next 24 h, one to three other 20-mL blood cultures consisting of a single pair of aerobic and anaerobic bottles will have to be performed, spaced by a minimum of 30 minutes. Bottles will be incubated for 5 days or until positivity reported by the BacT/Alert 3D instrument.
fechas
| Verificado por última vez: | 07/31/2015 |
| Primero enviado: | 07/27/2015 |
| Inscripción estimada enviada: | 08/03/2015 |
| Publicado por primera vez: | 08/05/2015 |
| Última actualización enviada: | 08/03/2015 |
| Última actualización publicada: | 08/05/2015 |
| Fecha de inicio real del estudio: | 11/30/2010 |
| Fecha estimada de finalización primaria: | 11/30/2012 |
| Fecha estimada de finalización del estudio: | 11/30/2012 |
Condición o enfermedad
Intervención / tratamiento
Procedure: Single-sampling strategy vs multi-sampling strategy for the diagnosis of bacteremia
Fase
Grupos de brazos
| Brazo | Intervención / tratamiento |
|---|---|
| Experimental: Multi-sampling strategy 2 or 3 blood cultures in 24 hours worked at ½ hour intervals with seeding at least a pair of flasks, aerobic and anaerobic, by blood culture. | |
| Active Comparator: Single-sampling strategy 1 single dose of venous blood 30ml ± 10ml with seeding 4 blood culture bottles (aerobic and anaerobic 2 2). |
Criterio de elegibilidad
| Edades elegibles para estudiar | 18 Years A 18 Years |
| Sexos elegibles para estudiar | All |
| Acepta voluntarios saludables | si |
| Criterios | Inclusion Criteria: - Patient who is at least 18 years - Patients admitted to an emergency department of a three CHU Caen, Lille, Rouen - Patient with clinical justifying the realization of blood cultures (as good practice recommendations) - Patients who received information about the study or if his legal representatives or his close entourage - Patient not objecting to the venipuncture Exclusion Criteria: - Patient who direct venipuncture is impossible - Patient refusing venipuncture - Patient aged under 18 - Patient with impaired vigilance and not accompanied by a family member or a trusted person may receive clear information protocol - Vulnerable Patient and not accompanied by a family member or a trusted person may receive clear information protocol |
Salir
Medidas de resultado primarias
1. Rate of pathogens identified by each strategy [baseline]
Medidas de resultado secundarias
1. Proportion of blood cultures contaminated in each strategy [baseline]
