Acupuncture in Palliative Cancer Care
Palabras clave
Abstracto
Descripción
Patients with advanced cancer suffer from many symptoms which dramatically reduce their Quality of Life (QOL). There have been significant improvements in the management of pain, nausea and constipation, but other common symptoms such as fatigue, anxiety, depression, and a lack of well-being are not readily addressed by conventional therapies. As cancer patients usually present with numerous symptoms, it would be important to try to address all of these globally, instead of only treating individual symptoms that respond well to conventional therapy. Attempts at controlling individual symptoms can also give rise to iatrogenic effects. One well known example is constipation occurring in patients who are on opiate analgesics. Successful treatment from the caregiver's perspective is often scored against each individual symptom that is being treated. From the patient's point of view, it is the interplay of the whole treatment package that succeeds or fails in improving his QOL
In an attempt at treating all of the patient's symptoms, research into the use of complementary and alternative medicine (CAM) has been conducted to determine the utility of these treatments in addressing the unmet needs of many patients with cancer. There is preliminary evidence that acupuncture in particular, is successful at improving many cancer and treatment associated symptoms.
Given the potential to improve symptom control and QOL, it is thought that acupuncture should be investigated to assess its effectiveness and feasibility in symptomatic patients with advanced cancer. Acupuncture should be compared against another intervention, so that the control group would also be receiving attention to their symptoms. As supportive care has been shown to be helpful in ameliorating symptoms in terminal care, acupuncture will be compared against this intervention. Sham acupuncture is not considered to be a good comparison for acupuncture as it is not well tested, and its effects are often indistinguishable from acupuncture. Recently however, some studies have reported the use of novel techniques that prevent acupuncture-naïve patients from distinguishing between acupuncture treatment and placebo. These techniques have yet to be independently validated.
Objectives: 1. To determine feasibility of recruiting patients and running a randomized study that involves acupuncture at the BCCA-VIC. 2. To gather enough data to support a grant application to fund a larger study to look at the effectiveness of acupuncture as adjunctive treatment for the management of symptoms associated with palliative cancer care.
fechas
Verificado por última vez: | 09/30/2010 |
Primero enviado: | 03/12/2006 |
Inscripción estimada enviada: | 03/12/2006 |
Publicado por primera vez: | 03/13/2006 |
Última actualización enviada: | 10/18/2010 |
Última actualización publicada: | 10/19/2010 |
Fecha de inicio real del estudio: | 05/31/2007 |
Fecha estimada de finalización primaria: | 02/29/2008 |
Fecha estimada de finalización del estudio: | 02/29/2008 |
Condición o enfermedad
Intervención / tratamiento
Procedure: Acupuncture
Behavioral: Nurse-led supportive care
Fase
Grupos de brazos
Brazo | Intervención / tratamiento |
---|---|
Active Comparator: Nurse-led supportive care Visit with a Palliative Care nurse once weekly for 4 weeks | Behavioral: Nurse-led supportive care 20-30 minutes of supportive attention from an experienced palliative nurse. |
Experimental: Acupuncture Patients received acupuncture once a week for 4 weeks. | Procedure: Acupuncture Insertion of sterile, single-use acupuncture needles at 10-20 points including PC.6, HT.7, St.36, SP.6, and LR.3. Needles were connected to an electrical stimulator to mimick traditional manual stimulation with alternating patterns of stimulation for 20 minutes. |
Criterio de elegibilidad
Edades elegibles para estudiar | 18 Years A 18 Years |
Sexos elegibles para estudiar | All |
Acepta voluntarios saludables | si |
Criterios | Inclusion Criteria: - patients receiving palliative therapy for incurable cancer - anticipated survival of at least 3 months - able to complete ESAS sheet unaided - ESAS of 5 or more in at least one of the following symptoms; fatigue, depression, anxiety and lack of wellbeing Exclusion Criteria: - refuse to receive weekly acupuncture for 4 weeks - refuse to receive nursing support for 4 weeks - known to have impaired clotting of blood |
Salir
Medidas de resultado primarias
1. The change in Edmonton Symptom Assessment Score (ESAS) after intervention (ESAS at baseline - ESAS at first follow up) will be analysed for each of the 4 symptoms (fatigue, anxiety, depression, a lack of well-being) under investigation. Results will be [undefined]
Medidas de resultado secundarias
1. Determine the % of patients suitable, and the % of patients who consent to be recruited. [undefined]
2. Determine the % of patients who complete all 4 intervention sessions. [undefined]
3. Determine the duration of change in ESAS after intervention (ESAS at second and third follow-up - ESAS at first follow up). [undefined]