Antioxidant Effect of Aged Garlic Extract
Palabras clave
Abstracto
fechas
| Verificado por última vez: | 07/31/2015 |
| Primero enviado: | 12/17/2013 |
| Inscripción estimada enviada: | 12/17/2013 |
| Publicado por primera vez: | 12/23/2013 |
| Última actualización enviada: | 08/16/2015 |
| Última actualización publicada: | 08/18/2015 |
| Fecha de inicio real del estudio: | 10/31/2013 |
| Fecha estimada de finalización primaria: | 03/31/2015 |
| Fecha estimada de finalización del estudio: | 03/31/2015 |
Condición o enfermedad
Intervención / tratamiento
Dietary Supplement: Placebo
Dietary Supplement: Aged garlic extract
Fase
Grupos de brazos
| Brazo | Intervención / tratamiento |
|---|---|
| Placebo Comparator: Placebo Smoker subjects take 6 capsules once a day for 4 weeks. | Dietary Supplement: Placebo |
| Experimental: Aged garlic extract Smoker subjects take 1.5 g of aged garlic extract in 6 capsules once a day for 4 weeks. | Dietary Supplement: Aged garlic extract |
| No Intervention: Non-smoker Oxidative status in non-smoker |
Criterio de elegibilidad
| Edades elegibles para estudiar | 40 Years A 40 Years |
| Sexos elegibles para estudiar | Male |
| Acepta voluntarios saludables | si |
| Criterios | Inclusion Criteria: - Smoking (at least 20 cigarettes per day) or non-smoking (more than 20 years) Exclusion Criteria: - Under medication for chronic disease - Garlic allergy - Engaging in vigorous exercise - Taking drugs or functional food that may possess antioxidant property - Participation in any clinical trial within 90 days of the commencement of the trial - Renal or hepatic dysfunction - Heart disease |
Salir
Medidas de resultado primarias
1. Urinary 8-hydroxydeoxyguanosine (8-OHdG) [Every 4 weeks (Overall 12 weeks)]
Medidas de resultado secundarias
1. High sensitive CRP [Every 4 weeks (Overall 12 weeks)]
2. Blood pressure [Every 4 weeks (Overall 12 weeks)]
3. Indices of the second derivative of photoplethysmogram (SDPTG) [Every 4 weeks (Overall 12 weeks)]
