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Clinical Outcome of Aortic Dissection

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Patrocinadores
Nanjing Medical University

Palabras clave

Abstracto

Aortic dissection refers to the blood in the aortic lumen entering the aortic mediastinum from the tear of the aortic intima, separating the mediastinum and extending along the long axis of the aorta to form the true and false separation state of the aortic wall. This disease is rare, and the incidence rate is 100 thousand to 200 thousand a year, with the peak age of 50-70 years old. 65%-70% patients died in the acute stage due to cardiac congestion and arrhythmia, so early diagnosis and treatment is very necessary. The aim of this study is analyze clinical outcome of Chinese patients with acute aortic dissection.

Descripción

Aortic dissection refers to the blood in the aortic lumen entering the aortic mediastinum from the tear of the aortic intima, separating the mediastinum and extending along the long axis of the aorta to form the true and false separation state of the aortic wall. Risk factors for aortic dissection included hypertension, cystic necrosis or degeneration of the middle aorta, hereditary connective tissue disease, congenital two-lobe active pulse valve, arteritis, aneurysm, atherosclerosis and iatrogenic injury, etc. The leading cause of aortic dissection is hypertension, and more than 75% of aortic dissection is associated with hypertension.Therefore, for hypertension patients to do a good job in the prevention and control of hypertension, pay attention to the regular use of antihypertensive drugs and monitoring blood pressure. In case of sudden chest and back lacerations, the patient should be immobilized in bed, contacted with an ambulance and sent to the hospital for emergency treatment, so as to avoid greater risks. The aim of this study is analyze clinical outcome of Chinese patients with acute aortic dissection.

fechas

Verificado por última vez: 04/30/2020
Primero enviado: 05/18/2020
Inscripción estimada enviada: 05/18/2020
Publicado por primera vez: 05/21/2020
Última actualización enviada: 05/18/2020
Última actualización publicada: 05/21/2020
Fecha de inicio real del estudio: 05/31/2020
Fecha estimada de finalización primaria: 12/30/2025
Fecha estimada de finalización del estudio: 12/30/2025

Condición o enfermedad

Aortic Dissection

Intervención / tratamiento

Other: observation

Fase

-

Criterio de elegibilidad

Edades elegibles para estudiar 18 Years A 18 Years
Sexos elegibles para estudiarAll
Método de muestreoNon-Probability Sample
Acepta voluntarios saludablessi
Criterios

Inclusion Criteria:

- Clinical diagnosis of acute aortic dissection

- Type A dissection

- Type B dissection

- Retrograde type B dissection

Exclusion Criteria:

- Aortic aneurysm

- Myocardial infarction

- Cerebral accident

- Active infection

- Unwillingness to cooperation with study procedures or follow-up visits

Salir

Medidas de resultado primarias

1. Operative mortality [30 days after treatment]

Operative mortality was defined as any death, regardless of cause, occurring whether within 30 days after surgery in or out of the hospital or after 30 days during the same hospitalization subsequent to the operation.

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