Cytokine Regulation of Periradicular Pain in Humans
Palabras clave
Abstracto
Descripción
This study evaluates whether periradicular exudate concentrations of cytokines differ in patients experiencing pain and mechanical allodynia due to pulpal necrosis with an acute exacerbation of a chronic apical periodontitis, as compared to patients with pulpal necrosis with chronic apical periodontitis, but no pain or mechanical allodynia
fechas
| Verificado por última vez: | 02/29/2012 |
| Primero enviado: | 09/12/2005 |
| Inscripción estimada enviada: | 09/12/2005 |
| Publicado por primera vez: | 09/21/2005 |
| Última actualización enviada: | 03/06/2012 |
| Última actualización publicada: | 03/08/2012 |
| Fecha de inicio real del estudio: | 09/30/2002 |
| Fecha estimada de finalización primaria: | 05/31/2008 |
| Fecha estimada de finalización del estudio: | 05/31/2008 |
Condición o enfermedad
Fase
Criterio de elegibilidad
| Edades elegibles para estudiar | 16 Years A 16 Years |
| Sexos elegibles para estudiar | All |
| Método de muestreo | Non-Probability Sample |
| Acepta voluntarios saludables | si |
| Criterios | Inclusion Criteria: 1. Patient must be at least 16 years of age. 2. Clinical indication for Non-Surgical Root Canal Therapy (NSRCT). 3. 1st or 2nd maxillary or mandibular molar 4. Diagnosis must be Chronic Apical Periodontitis (CAP) with or without symptoms. 5. Intact, mature apices. 6. ASA I or II Exclusion Criteria: 1. Failure to meet any of the above 2. Previous NSRCT 3. Previous pulpotomy or pulpectomy 4. Suppurative apical periodontitis 5. Patients taking medications which can affect their pain rating or medications which effect their immune system ( such as glucocorticoids) |
