Effect of Protein Composition on Gastric Emptying
Palabras clave
Abstracto
Descripción
Several factors in nutrition are known to affect gastric emptying rate, such as energy content, temperature, viscosity etc. In infants the protein composition affects gastric emptying. Children with cerebral pasly commonly have foregut dysmotility - with nausea, vomiting, feeding intolerance and gastroesophageal reflux. Tube feedings, usually based on cows milk are commonly used.
Our hypothesis is that the source and thus protein composition of feeding affects gastric emptying rate and electrofysiology.
Using four different tube feedings, standardized for content of fat, glucose and calories, we will measure gastric emptying rate using C13 octanoic acid as well as electrogastrography will be recorded. The protein modules are derived from casein, whey/casein mixture, hydrolyzed whey and aminoacids. Children with cerebral paresis and gastrostomy will be included. Each serves as his / her own control.
The primary endpoint is gastric emptying rate, the secondary endpoint electrogastrography.
fechas
| Verificado por última vez: | 05/31/2006 |
| Primero enviado: | 06/26/2006 |
| Inscripción estimada enviada: | 06/26/2006 |
| Publicado por primera vez: | 06/27/2006 |
| Última actualización enviada: | 06/26/2006 |
| Última actualización publicada: | 06/27/2006 |
| Fecha de inicio real del estudio: | 07/31/2006 |
| Fecha estimada de finalización del estudio: | 11/30/2007 |
Condición o enfermedad
Intervención / tratamiento
Procedure: Nutrition composition
Fase
Criterio de elegibilidad
| Edades elegibles para estudiar | 1 Year A 1 Year |
| Sexos elegibles para estudiar | All |
| Acepta voluntarios saludables | si |
| Criterios | Inclusion Criteria: Cerebral paresis, user of tube feedings through gastrostomy - Exclusion Criteria: Use of valproic acid (interferes with breath test). Age >16 y. - |
Salir
Medidas de resultado primarias
1. Gastric emptying, measured by octanoic acid breath test. [undefined]
Medidas de resultado secundarias
1. Electrogastrography [undefined]
