Hepcidin Behavior in Patients With Obesity and Bariatric Surgery
Palabras clave
Abstracto
Descripción
During the visit in the obesity clinic, eligible patients will be approached for participation by the sub-investigator. Interested patients will receive information regarding the study and receive the information sheet containing the informed consent form. After signing the informed consent form, general information will be collected regarding medical and demographic data using a short questionnaire. Additional questionnaires regarding demographics and menstrual cycle will be collected. Anthropometric measurements will be collected for the determination of the length, weight, hip circumference, waist circumference and body composition. Finally, blood samples will be collected for the determination of iron and inflammation related markers.
fechas
| Verificado por última vez: | 05/31/2019 |
| Primero enviado: | 06/16/2019 |
| Inscripción estimada enviada: | 06/17/2019 |
| Publicado por primera vez: | 06/18/2019 |
| Última actualización enviada: | 12/22/2019 |
| Última actualización publicada: | 12/25/2019 |
| Fecha de inicio real del estudio: | 01/07/2019 |
| Fecha estimada de finalización primaria: | 05/31/2020 |
| Fecha estimada de finalización del estudio: | 05/31/2020 |
Condición o enfermedad
Intervención / tratamiento
Other: Blood sampling
Fase
Grupos de brazos
| Brazo | Intervención / tratamiento |
|---|---|
| Patients with obesity In 100 patients with obesity, blood samples will be collected. | |
| Patients with a Sleeve Gastrectomy In 100 patients with a Sleeve Gastrectomy, blood samples will be collected. | |
| Patients with a Roux-en-Y Gastric Bypass In 100 patients with a Roux-en-Y Gastric Bypass, blood samples will be collected. |
Criterio de elegibilidad
| Edades elegibles para estudiar | 18 Years A 18 Years |
| Sexos elegibles para estudiar | All |
| Método de muestreo | Probability Sample |
| Acepta voluntarios saludables | si |
| Criterios | Inclusion Criteria: - The patient has to be 18 years or older - Written informed consent has to be obtained after being informed on all aspects of the study - The patient has a BMI > 30 kg/m² OR There has to be at least one year between the primary RYGB and the participation in the study OR There has to be at least one year between the primary SG and the participation in the study Exclusion Criteria: - Patients younger than 18 years old - Women who are pregnant or are breastfeeding - Post-menopausal women, defined as at least 12 months of amenorrhea after the final menstrual period - Inability to follow the procedures of the studies due to language problems - Patients who have had more than one bariatric surgery |
Salir
Medidas de resultado primarias
1. Serum hepcidin concentration [Study visit 1 day]
Medidas de resultado secundarias
1. Hemoglobin concentration [Study visit 1 day]
2. Mean corpuscular volume [Study visit 1 day]
3. Iron concentration [Study visit 1 day]
4. Ferritin concentration [Study visit 1 day]
5. Transferrin concentration [Study visit 1 day]
6. Transferrin saturation [Study visit 1 day]
7. C-reactive protein [Study visit 1 day]
