Influence of Tobacco Use on Cannabis Use
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EstadoReclutamiento
Patrocinadores
New York State Psychiatric Institute
Colaboradores
National Institute on Drug Abuse (NIDA)
ENSAYO CLÍNICO: NCT03766971
BioSeek: nct03766971
Palabras clave
Abstracto
Cannabis smokers who also smoke tobacco cigarettes have markedly higher rates of cannabis relapse relative to those who do not use tobacco. There is a clear need to develop and evaluate interventions for dual tobacco and cannabis users. The investigators of this study have previously shown that the co-use of tobacco cigarettes contributes to the maintenance of daily cannabis use, and that age of cigarette onset is a critical predictor of treatment outcome. Short-term tobacco cessation may suffice in altering cannabis relapse rates in later-onset cigarette smokers, while a longer period of tobacco cessation may be needed for earlier-onset smokers. In the current study, a human laboratory model will be utilized to determine whether cannabis relapse varies as a function of tobacco cessation duration and age of tobacco use onset.
fechas
Verificado por última vez: | 01/31/2020 |
Primero enviado: | 12/03/2018 |
Inscripción estimada enviada: | 12/04/2018 |
Publicado por primera vez: | 12/05/2018 |
Última actualización enviada: | 02/18/2020 |
Última actualización publicada: | 02/20/2020 |
Fecha de inicio real del estudio: | 01/31/2020 |
Fecha estimada de finalización primaria: | 11/29/2024 |
Fecha estimada de finalización del estudio: | 11/29/2024 |
Condición o enfermedad
Cannabis Use
Tobacco Use
Intervención / tratamiento
Behavioral: 7 days of Tobacco Cessation
Behavioral: 21 days of Tobacco Cessation
Drug: Cannabis
Fase
Fase 2
Grupos de brazos
Brazo | Intervención / tratamiento |
---|---|
Experimental: Early-onset Cigarette Smokers Participants who began smoking cigarettes earlier in life (<16 years old) will be randomized to 7 or 21 days of tobacco cessation. | |
Experimental: Late-onset Cigarette Smokers Participants who began smoking cigarettes later in life (>16 years old) will be randomized to 7 or 21 days of tobacco cessation. |
Criterio de elegibilidad
Edades elegibles para estudiar | 18 Years A 18 Years |
Sexos elegibles para estudiar | All |
Acepta voluntarios saludables | si |
Criterios | Inclusion Criteria: - Males and non-pregnant females aged 18-60 years old - Use cannabis - Smoke tobacco cigarettes - Medically and psychologically healthy Exclusion Criteria: - Regular drug use other than cannabis - Current pregnancy/lactation |
Salir
Medidas de resultado primarias
1. Cannabis self-administration [During 9-day inpatient phase]
Number of cannabis cigarettes participant chooses to smoke.