Iron-Deficiency Anemia in Infants in Two Weekly Programs
Palabras clave
Abstracto
Descripción
Some studies have shown satisfactory results in reducing the prevalence of iron deficiency using weekly doses of ferrous sulfate, thereby avoiding these side effects. This deficiency is the most common nutritional disorder during childhood and does not only affect individuals from developing countries but also those from industrialized nations.
For infants with ages between six and 24 months, iron supplementation is the main treatment for iron deficiency. In this age range the prevalence of anemia is at least 20%. However, studies have shown a low rate of compliance by mothers during the recommended period, which may be caused by a lack of care or, more probably, due to the side effects caused by long-term daily ferrous sulfate supplementation, which include nausea, vomiting, diarrhea, staining of teeth and abdominal pain.
This specific study is randomized clinical trial study, achieved in a government healthcare clinic in Sao Jose do Rio Preto, Sao Paulo, Brazil. This study was carried out using two intervention groups. All children received 12 weekly doses of 25 mg of elemental iron, either administered in the government healthcare clinic or at the children's home.
The study showed treatment compliance in both groups. Prevalence of anemia for all children was 75% at the beginning of supplementation and 46.3% at the end of the period (p < 0.0005). Reduction rate for anemic children was 38.3%. Average increases in hemoglobin concentration levels were 0.75 g/dL and 0.65 g/dL, respectively, for home interventions and healthcare clinic administration (p < 0.00005).
fechas
Verificado por última vez: | 03/31/2008 |
Primero enviado: | 04/02/2008 |
Inscripción estimada enviada: | 04/02/2008 |
Publicado por primera vez: | 04/08/2008 |
Última actualización enviada: | 04/02/2008 |
Última actualización publicada: | 04/08/2008 |
Fecha de inicio real del estudio: | 03/31/2003 |
Fecha estimada de finalización primaria: | 08/31/2003 |
Fecha estimada de finalización del estudio: | 12/31/2003 |
Condición o enfermedad
Intervención / tratamiento
Drug: A
Fase
Grupos de brazos
Brazo | Intervención / tratamiento |
---|---|
Active Comparator: A For infants with ages between six and 24 months, iron supplementation is the main treatment for iron deficiency.This study was carried out using two intervention groups. All children received 12 weekly doses of 25 mg of elemental iron.
Group 1 administered in the government healthcare clinic. Group 2 administered children's home.
The study showed treatment compliance in both groups. | Drug: A Iron supplementation. |
Criterio de elegibilidad
Edades elegibles para estudiar | 6 Months A 6 Months |
Sexos elegibles para estudiar | All |
Acepta voluntarios saludables | si |
Criterios | Inclusion Criteria: - Ages ranging between six and 24 months old Exclusion Criteria: - Positive results for the Guthrie test - Use of ferrous sulfate supplements - Infections process at the time of first consultation |
Salir
Medidas de resultado primarias
1. Test (serum hemoglobin) [assessed at the before of the treatment period]
Medidas de resultado secundarias
1. Test (serum hemoglobin) [assessed after 12 weekly with iron supplement]