The Relationship Between Morbid Obesity and Carotid Artery Stenosis
Palabras clave
Abstracto
Descripción
The investigators hypothesis is that there is a direct relationship between morbid obesity and carotid artery stenosis. The investigators hypothesize that metabolic/Bariatric surgery improves the stenosis in the carotid artery.
This is a prospective comparative study on the candidates for metabolic/Bariatric surgery in the bariatric center, Emek Medical Center, Afula, Israel. The investigators will compare the candidate for metabolic surgery with metabolic syndrome risk factors to the ones without metabolic syndrome risk factors.
The assessment of the carotid artery will be done by Ultrasound Doppler before surgery and 6, 12 and 24 month post surgery.
fechas
| Verificado por última vez: | 09/30/2017 |
| Primero enviado: | 09/30/2017 |
| Inscripción estimada enviada: | 10/04/2017 |
| Publicado por primera vez: | 10/10/2017 |
| Última actualización enviada: | 02/24/2018 |
| Última actualización publicada: | 02/26/2018 |
| Fecha de inicio real del estudio: | 05/31/2018 |
| Fecha estimada de finalización primaria: | 03/31/2019 |
| Fecha estimada de finalización del estudio: | 06/30/2020 |
Condición o enfermedad
Intervención / tratamiento
Diagnostic Test: Ultrasound Duplex
Fase
Grupos de brazos
| Brazo | Intervención / tratamiento |
|---|---|
| Metabolic syndrome risk factors Candidates for bariatric surgery who have metabolic syndrome risk factors will be evaluated by Ultrasound duplex before the bariatric surgery and 6,12 and 24 months post surgery for Intimal-Media Thickness and Carotid artery velocity | |
| No metabolic Syndrome risk factors Candidates for bariatric surgery who lack metabolic syndrome risk factors will be evaluated by Ultrasound duplex before the bariatric surgery and 6,12 and 24 months post surgery for Intimal-Media Thickness and Carotid artery velocity |
Criterio de elegibilidad
| Edades elegibles para estudiar | 18 Years A 18 Years |
| Sexos elegibles para estudiar | All |
| Método de muestreo | Non-Probability Sample |
| Acepta voluntarios saludables | si |
| Criterios | Inclusion Criteria: • Candidates for first bariatric surgery Exclusion Criteria: - Smokers or past smokers - Patients who are post carotid artery intervention |
Salir
Medidas de resultado primarias
1. Correlation between morbid obesity and carotid artery stenosis [24 months post surgery]
Medidas de resultado secundarias
1. Changes in Intimal -media thickness [Before bariatric surgery, and 6,12,24 months after the surgery]
2. Changes in the carotid artery velocity [Before bariatric surgery, and 6,12,24 months after the surgery]
