[Chemical constituents from the root of Ilex cornuta].
Palabras clave
Abstracto
OBJECTIVE
To investigate the chemical constituents of the root of Ilex cornuta.
METHODS
The constituents were isolated by silica gel, Sephadex LH-20 gel, medium pressure column and semi-preparative liquid chromatography and their structures were elucidated by chemical properties and spectroscopic analyses.
RESULTS
Ten compounds were isolated and their structures were identified as: Oleanolic acid (1), Siaresinolic acid (2), 28-O-beta-D-glucopyranosyl pomolic acid (3), Pomolic acid (4), 3beta-O-alpha-L-arabinopyranosyl rotundic acid (5), 3beta-[alpha-L-arabinopyranosyl) oxy]-19alpha-hydroxyolean-12-en-28-oic acid 28-beta-D-glucopyranosyl ester (6), Lup-20(29)-en-3beta,23-diol (7), Chikusetsusaponin IV a butyl ester (8), Oleanolic acid-3-O-( 6'-O-methyl)-beta-D-glucuronopyranoside (9), 3-O-[(alpha-L-arabinopyranosyl)-(1 --> 2)]-beta-D-glucuronopyranosyl-(6'-O-methyl-ester)-olean-12-ene-28-olic acid (10).
CONCLUSIONS
Compounds 7 - 10 are isolated from this genus for the first time, and compounds 2 - 6 are isolated from this plant for the first time.