[Chemical constituents from the twigs and leaves of Melodinus suaveolens].
Palabras clave
Abstracto
OBJECTIVE
To investigate the chemical constituents from the twigs and leaves of Melodinus suaveolens.
METHODS
The chemical consituents were separated and purified by column chromatographies with silica gel, Sephadex LH-20, ODS and RP-HPLC. Their structures were identified on the basis of physicochemical properties and spectral analysis.
RESULTS
Ten compounds were isolated and identified as ursolic acid (1), 22alpha-hydroxyursolic acid (2), betulinic acid (3), betulinic alcohol (4), 2,3-dihydroxy-1-(4-hydroxy-3-methoxyphenyl) -propan-1-one (5), (+)-isolariciresinol (6), (+/-)-liquiritigenin (7), salicylic acid (8), beta-sitosterol (9) and daucosterol (10), respectively.
CONCLUSIONS
NMR spectra of compound 2 are reported for the first time, and compounds 1 - 10 are firstly isolated from this plant.
