[Chemical constituents of Centipeda minima].
Palabras clave
Abstracto
OBJECTIVE
To study the chemical constituents from Centipeda minima.
METHODS
The compounds were separated and purified by silica gel, reserved phase silica gel and Sephadex LH-20 gel column chromatography. Their structures were identified on the basis physicochemical property and spectral analysis.
RESULTS
Four chemical constituents were separated from ethyl acetate extracts and five chemical constituents were separated from n-butanol extracts of C. minima and identified as (2R,3R)-(+)-7,4'-di-O-methyldihydrokaempferol (1), iristectorin A (2), 4',5,8-trihydroxy-7-methoxyisoflavone (3), 3-trimethoxyquercetin (4), 3-O-caffeoyl-alpha-glueopyranose (5), 3-O-caffeoyl-beta-glucopyranose (6), quercetin (7), epipinoresinol (8) and hispidulin (9).
CONCLUSIONS
Compounds 1-3, 5-6, 8 and 9 are separated from this genus for the first time.