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Phytochemical investigation of the stem of Morus notabilis led to the isolation and characterization of 10 compounds of 2-arylbenzofurans (1-10), including two new compounds, (2'R)-2',3'-dihydro-2'-(1-hydroxy-1-methylethyl)-2,6'-bibenzofuran-6,4'-diol (1) and
Two novel 2-arylbenzofuran dimers, morusyunnansins A and B (1 and 2), two new biflavonoids, morusyunnansins C and D (3 and 4), two new flavans, morusyunnansins E and F (5 and 6), and four known flavans (7-10) were isolated from the leaves of Morus yunnanensis. Compounds 5-8 showed potent inhibitory
Oxidation and enzymatic browning of food can affect nutritional quality, physical and chemical properties, and food safety, emphasizing the utmost importance of discovering new natural antioxidants and anti-browning agents. The present study aimed to characterize the antioxidant and anti-browning
Ten new geranylated 2-arylbenzofuran derivatives, including two monoterpenoid 2-arylbenzofurans (1 and 2), two geranylated 2-arylbenzofuran enantiomers (3a and 3b), and six geranylated 2-arylbenzofurans (4-9), along with four known 2-arylbenzofurans (10-13) were isolated from the root bark of Morus
Four new 2-arylbenzofuran derivatives, moracins V-Y (1-4), together with two known compounds, moracin N (5) and moracin P (6), were isolated from the leaves of Morus alba L. Their structures were elucidated by spectroscopic analysis. Moracins X (3) and Y (4) represent unusual substituted group
Among the 2-arylbenzofuran derivatives isolated from Morus alba, the farnesylated 2-arylbenzofuran is a rarer constituent. The derivative has been reported to exert anti-obesity effect; however, its inhibitory effect on protein tyrosine phosphatase 1B (PTP1B) has not been investigated. In the
A new 2-arylbenzofuran compound, 5-dehydroxy-moracin U (1), along with 10 known compounds (2-11), were isolated from cell cultures of Morus alba. Their structures were elucidated on the basis of extensive spectroscopic analyses. The anti-inflammatory activity assay of 1-8 showed that 2 and 8
Five new 2-arylbenzofuran derivatives wittifurans A-C, F and G (1-5) have been isolated from the stem bark of Morus wittiorum. Their structures were determined on the basis of spectroscopic analysis. Compounds 1, 3-5 were evaluated for their antioxidant and anti-inflammatory activities respectively.
Investigation of an ethanol extract from the stem bark of Morus wittiorum led to the isolation of five new 2-arylbenzofuran derivatives that were named wittifuran S, wittifuran T, wittifuran V, wittifuran W and wittifuran X (1-5). Structures were determined on the basis of spectroscopic analysis.
Three new 2-arylbenzofurans named wittifuran H, wittifuran I and wittifuran U (1-3) were obtained during our ongoing investigation of an ethanol extract from the stem bark of Morus wittiorum. Their structures were elucidated on the basis of spectroscopic data. Compound 2 displayed potent
A new 2-arylbenzofuran, sanggenofuran B (3',5'-dihydroxy-6-methoxy-4'-prenyl-2-arylbenzofuran), from the root bark of Chinese Morus cathayana is reported.
Four new 2-arylbenzofuran derivatives, cathafurans A (1), B (2), C (3), and D (4), were isolated from the stem bark of Morus cathayana. Their structures were determined by spectroscopic methods. Compounds 2 and 3 exhibited moderate activities against five human cancer cell lines, with IC(50) values
The investigation on the stem bark of Morus wittiorum was carried out to find its chemical constituents possessing anti-oxidative activity. The isolation and purification were performed by various chromatographies such as silica gel, Sephadex LH-20, RP-C18 column chromatography and so on. Based on
Nine 2-arylbenzofurans isolated from Morus species were tested for their antimicrobial activities against methicillin-sensitive Staphylococcus aureus (MSSA), methicillin-resistant S. aureus (MRSA), Micrococcus luteus, Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae and Pseudomonas
Ethyl acetate- and n-butanol-soluble fractions of the leaves of Morus insignis showed a significant hypoglycemic activity on streptozotocin (STZ)-induced hyperglycemic rats. From these hypoglycemic activity-showing fractions, two new compounds, mulberrofuran U (2) and moracin