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Safranal-sorafenib combination therapy for liver cancer
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TECHNICAL FIELD
The present invention relates to therapeutic formulations and methods for treating liver cancer including safranal and sorafenib.
BACKGROUND
Despite all efforts, more people are diagnosed with hepatocellular carcinoma (HCC); the most common type of primary liver cancer and the second
Retinal cyclodextrin acetals and hemiacetals for treating skin complexion disorder
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BACKGROUND OF THE INVENTION
The enhancement of physical appearance occupies greater focus in human life than nearly all other daily life-related actions. There are far more consumer products available for the beautification of human body than for the treatment of human ailments. The improvement of
Imidazolyl-cyclic acetals
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This invention is directed to imidazolyl-cyclic acetals, their preparation, pharmaceutical compositions containing these compounds, and their pharmaceutical use in the treatment of disease states capable of being modulated by the inhibition of TNF.
Tumour necrosis factor (TNF) is an important
Telomerase inhibitors
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BACKGROUND OF THE INVENTION
1. The Field of the Invention
The present invention relates to human telomerase, a ribonucleoprotein enzyme involved in human telomere DNA synthesis, and to compounds that inhibit telomerase activity. The invention provides methods, compounds and compositions relating to
Gem-difluorinated C-glycoside compounds derived from podophyllotoxin, their preparation and their applications
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates to a method for the synthesis of gem-difluorinated C-glycoside compounds derived from podophyllotoxin. It more particularly, but not exclusively, applies to the preparation of compounds which may be notably used in oncology
Acyclic monoterpenoid derivatives
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BACKGROUND OF THE INVENTION
Cell proliferation requires the transfer of mevalonate pathway intermediates to a group of proteins, small G-proteins and the nuclear lamins among others. Agents targeted to the inhibition of the transfer process (farnesylation, geranylgeranylation), e.g., farnesyl
Process for the preparation of macrocyclic metalloprotease inhibitors
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FIELD OF THE INVENTION
The present invention relates to processes for the preparation of macrocyclic molecules containing anti-succinate residues which inhibit metalloproteinases such as aggrecanase, and the production of tumor necrosis factor (TNF). The anti-succinates are formed by an Ireland
Process for the preparation of macrocyclic metalloprotease inhibitors
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FIELD OF THE INVENTION
The present invention relates to processes for the preparation of macrocyclic molecules containing anti-succinate residues which inhibit metalloproteinases such as aggrecanase, and the production of tumor necrosis factor (TNF). The anti-succinates are formed by an Ireland
Method for preparing novel transcription factors and use
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BACKGROUND OF THE INVENTION
The present invention relates to a method for preparing novel transcription factors which modify the procedure of transcription of gene information in a messenger RNA and their use.
The leading cause of death in developed countries other than Japan is ischemic heart
Chemotherapeutic compositions
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TECHNICAL FIELD
The present invention relates to the treatment of gastrointestinal disease, and/or cancer, and a method of weight gain, via the ingestion of polymeric compositions in humans, animals or birds in need of said treatment.
BACKGROUND ART
Under the conditions of intensive pig-rearing,
Trioxane monomers and dimers
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BACKGROUND
Malaria is one of the world's most widespread infectious diseases. Ridley et al., 2002. Much effort is currently being devoted to develop effective vaccines to prevent humans from becoming infected with malaria parasites. LeBlanc et al., 2008; Troye-Blomberg et al., 2007. Treatment of
Synthetic process toward total synthesis of eleutherobin and its analogues and uses thereof
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BACKGROUND OF THE INVENTION
Throughout this application, various references are referred to within parentheses. Disclosures of these publications in their entireties are hereby incorporated by reference into this application to more fully describe the state of the art to which this invention
Use of indole-3-acetic acid derivatives in medicine
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This invention relates to derivatives of indole-3-acetic acid (IAA) and their use as pharmaceuticals, in particular for treating neoplastic disease.
Indole-3-acetic acid: ##STR2##
is a naturally-occurring plant growth phytohormone which has been extensively studied. As long ago as 1956, its effects
Method for synthesis of bifunctional chelating agents-peptides
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FIELD OF THE INVENTION
The present invention relates to a novel synthesis of octreotide by solid phase synthesis and conjugated peptides using bifunctional chelating agents. In particular, the present invention relates to linkage, cyclization, and radioactive isotope labelling such as by In-111 or
Bioactive acetogenins and derivatives
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FIELD OF INVENTION
This invention relates to the isolation, identification, derivatization, and use of natural products. More particularly this invention is directed to substantially pure forms of cytotoxic Annonaceous acetogenins and certain ester and cyclized ether acetogenin
La base de datos de hierbas medicinales más completa respaldada por la ciencia
- Funciona en 55 idiomas
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- Reconocimiento de hierbas por imagen
- Mapa GPS interactivo: etiquete hierbas en la ubicación (próximamente)
- Leer publicaciones científicas relacionadas con su búsqueda
- Buscar hierbas medicinales por sus efectos.
- Organice sus intereses y manténgase al día con las noticias de investigación, ensayos clínicos y patentes.
Escriba un síntoma o una enfermedad y lea acerca de las hierbas que podrían ayudar, escriba una hierba y vea las enfermedades y los síntomas contra los que se usa.
* Toda la información se basa en investigaciones científicas publicadas.
