this group will receive ginger drink made by dissolving 4g ginger powder in plain water once a day for continuous 5 days.

this group will receive ginger drink made by dissolving 4g ginger powder in plain water twice a day for continuous 5 days.

Platelets Dysfunction

Hematological Diseases

Ginger drink

King Abdulaziz Medical City - National Guard Hospital

Daily Ginger Drinking and Platelet Function

The Effect of Daily Ginger Drinking on Platelet's Function in the Saudi Population

King Abdullah International Medical Research Center

Take two capsules, twice daily before breakfast and dinner

Blood Pressure

Onion-Pumpkin Extract

The Effects of the Onion-Pumpkin Extract on Blood Pressure

The Effects of the Onion-Pumpkin Extract on Blood Pressure: An Open-label, Adaptive-design, Pilot Study

Medicus Research, LLC

Placebo 1.2 g per day for 12 weeks, followed by a second treatment period with aged garlic extract during 12 more weeks.

Aged garlic extract, 1.2 g per day for 12 weeks, followed by a second treatment period with placebo during 12 more weeks.

Metabolic Syndrome

Aged garlic extract, 1.2 g per day for 12 weeks

aged garlic extract

Placebo

Medicine School, Universidad de Santander

Trial of Supplementation With Aged Garlic Extract to Improve Endothelial Function in Patients With Metabolic Syndrome

A PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF THE SUPPLEMENTATION WITH KIOLIC® IN PATIENTS WITH DIAGNOSIS OF METABOLIC SYNDROME TO IMPROVE ENDOTHELIAL FUNCTION AND INFLAMMATORY STATE. "KYMES"

The flow mediated vasodilation is a non-invasive diagnostic test using high-resolution doppler ultrasound, that measures the changes in diameter of the brachial artery in response to increased blood flow (reactive hyperemia).
The plasma levels of nitrites/nitrates will be determined by immunoassay (R&D Systems, Inc)

During the initial and follow-up visits, a blood sample will be taken to determine C-reactive protein by high sensitivity chemiluminescent immunometric assay (IMMULITE 1000, DPC, Los Angeles, CA) and Interleukin-6 by immunoassay (Biosource International, Camarillo, CA)

Blood samples will be taken at the initial and follow-up visits (12,24 weeks) to determine blood glucose by automatic colorimetric method (Baker System 9120 AX, Biochem Immunosystem, Allentown, PA)and insulin plasma levels by high sensitivity chemiluminescent immunometric assay (IMMULITE 1000, DPC, Los Angeles, CA).

Anthropometric measures will be determined at the initial and follow-up visits (12,24 weeks).

Blood samples will be taken at the initial and follow-up visits (12,24 weeks) to determine adiponectin by Human Adiponectin/Acrp30 Quantikine ELISA (R&D Systems, USA)

Patricio López-Jaramillo

Universidad de Santander

Instituto de Salud de Bucaramanga

AGE (1200 mg) and CoQ10 (120 mg)
This is a combination of aged garlic extract and co-enzyme Q10

Patients randomized to oral AGE (1200 mg) and CoQ10 (120 mg)

Aged Garlic Extract and Coenzyme Q10

Total

Sex: Female, Male

Region of Enrollment

progression of coronary artery calcium deposits as determined by computed tomography as measured by the Agatston score: The Agatston score was calculated by multiplying the lesion area (mm^2) by a density factor. The density was measured in Hounsfield units, and score of 1 for 130-199 HU, 2 for 200-299 HU, 3 for 300-399 HU, and 4 for 400 HU and greater The endpoint is the mean change (end of study value - baseline value) in each group.

Rate of Change in Total Coronary Calcium Scores by Computed Tomography

1.Plasma Lipids: Total Plasma Cholesterol and Triglycerides, LDL-Cholesterol, HDL-Cholesterol, and VLDL-Cholesterol Determined by the Precipitation Method; 2. Endothelial Markers and Inflammation: C-reactive Protein and Homocysteine, as Well as GSH

Overall Study

Dr Matthew Budoff

Coronary Atherosclerosis

Coronary Artery Calcification

Coronary Stenosis

Aged garlic extract and Coenzyme Q10

Contact Drs Budoff or Laidlaw for further information

allium sacculiferum/infartarse

Daily Ginger Drinking and Platelet Function

The Effects of the Onion-Pumpkin Extract on Blood Pressure

Trial of Supplementation With Aged Garlic Extract to Improve Endothelial Function in Patients With Metabolic Syndrome

Firefighter Aged Garlic Extract Investigation With CoQ10 as a Treatment for Heart Disease (FAITH)

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