Intervention: Oral challenge of Fructose+Glucose Beverage 1:1, 3g/kg

Adolescent Obesity

The intervention is an oral sugar challenge with blood sampling over three hours.

Fructose + Glucose Beverage

Weill Cornell Medicial College

Fructose-induced Hepatic De Novo Lipogenesis in Adolescents With Obesity

In the 2 study groups: a comparison of the increase in VLDL TG palmitate over 3 hours after ingestion of a beverage made with fructose and glucose.
after an oral challenge of fructose+glucose

In the two study groups: a comparison of other markers of carbohydrate and fatty acid metabolism (i.e. VLDL and total TG, cholesterol, apolipoprotein B, insulin, and glucose) before and after the oral sugar challenge.
2) To correlate these markers with the increase in VLDL TG %16:0.

The Rogosin Institute

Weill Medical College of Cornell University

University of Missouri-Columbia

Participant will receive a blueberry drink containing 18 g of fructose and 14 g of glucose.

Participant will receive a blueberry drink and a slice of pizza (170 grams; 22 g protein, 20 g fat and 50 g carbohydrate; 425 kCal)

Participant will receive a Soft beverage (Coca-cola containing 17,5 g fructose and 17,5 g glucose)

Participant will receive a Soft beverage and a slice of pizza (170 grams; 22 g protein, 20 g fat and 50 g carbohydrate; 425 kCal)

Participant will receive a drink containing 35 g of fructose

Participant will receive a drink containing 35 g of fructose and a slice of pizza (170 grams; 22 g protein, 20 g fat and 50 g carbohydrate; 425 kCal)

Chronic Kidney Diseases

Diabetes Mellitus, Type 2

Blueberry drink

Participant receive blueberry drink and a slice of pizza

Blueberry and pizza

Participant receive a soft beverage drink

Soft beverage

Participant receive a soft beverage drink and a slice of pizza

Soft beverage and pizza

Participant receive a drink containing fructose

Fructose

Participant receive a fructose drink and a slice of pizza

Fructose and pizza

Karolinska University Hospital

Effect of Acute Fructose Load in Human

The Effect of Acute Fructose Load in Patients With Chronic Kidney Disease and Patients With Type 2 Diabetes Compared to Healthy Subjects

Change in uric acid after intervention compared to the levels Before the intervention

Neda Rajamand Ekberg

M.D.,Ph.D

Interventional study. Participant will on sex different occasions receive drinks containing fructose (fructose drink, coca-cola or blueberry drink) with and without the addition of a high-fat meal

Isocaloric fructose restricted diet for 10 days

Obesity

Metabolic Syndrome

fructose restriction diet

UCSF

Metabolic Impact of Fructose Restriction in Obese Children

We anticipate fructose restriction to reduce intrahepatic fat, exclusive of calories

We anticipate fructose restriction will improve insulin sensitvity exclusive of calories

University of California, San Francisco

Touro University

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

First injection in human, on 6 healthy volunteers, sequentially : volunteer number1, then volunteers n°2 to n° 6, before infusion in type 2 diabetic patients.

After completion of the study for the 6 healthy volunteers, infusion in 6 type 2 diabetic patients.

Type 2 Diabetes Mellitus

injection of 6-DIG

Service de Biophysique et Médecine Nucléaire, CHU de Grenoble

Development of a Fast Measurement Technique of Insulin Resistance in Human

Development of a Fast Measurement Technique of Insulin Resistance in Human, With 123-6-deoxy-6 Iodo-D-glucose, a New Tracer of Glucose Transport

Assessment of tolerance to insulin resistance measurement technique with 6-DIG scintigraphy, in healthy volunteers
clinical tolerance to 6-DIG infusion
clinical and biological tolerance to insulin infusion
evaluation of dosimetry

scintigraphic measurement of glucose transport in heart before and after infusion of insulin

alpha fructose/obesidad

Fructose-induced Hepatic De Novo Lipogenesis in Adolescents With Obesity

Effect of Acute Fructose Load in Human

Metabolic Impact of Fructose Restriction in Obese Children

Development of a Fast Measurement Technique of Insulin Resistance in Human

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