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12 resultados
Diagnosis of gluten sensitive enteropathy and other autoimmunopathies
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RELATED APPLICATIONS
This application is a 35 U.S.C. .sctn.371 filing of International Application Number PCT/EP00/06025, entitled "Diagnosis of Gluten Sensitive Enteropathy and Other Autoimmunopathies" filed on Jun. 28, 2000, which claims priority to European Patent application 99111975.1, filed
Transgenic mouse models for diseases caused by mtDNA mutations and related methods
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FIELD OF THE INVENTION
The present invention relates generally to genetics and biomedical methodology and more particularly to the establishment and uses of a mouse model of disorders (e.g., age-related disorders, cardiac disease, muscle disease, cancer, etc.) caused by a mitochondrial DNA point
Methods for treating acromegaly and giantism with growth hormone antagonists
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FIELD OF THE INVENTION
This invention relates to novel muteins of growth hormone ("GH"), especially human growth hormone ("hGH"), which diminish, decrease or inhibit the growth of animals or otherwise diminish, decrease or inhibit the effects of endogenous GH by acting as an antagonist to growth
Adamantanamines and neramexane salts of thiomolybdic and thiotungstic acids
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FIELD OF THE INVENTION
The present invention concerns the preparation and uses of adamantanamines (e.g. memantine, amantadine and rimantadine) and neramexane(s) salts of thiomolybdic acids and thiotungstic acids. Their pharmaceutical compositions incorporate two complementary, bioavailable
Tetrahydroisoquinoline-3-carboxylic acid alkoxyguanidines as integrin antagonists
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BACKGROUND OF THE INVENTION
1. Field of the Invention The present invention relates to novel tetrahydroisoquinoline-3-carboxylic acid alkoxyguanidine compounds that are antagonists of alpha V (.alpha.v) integrins, for example .alpha..sub.v.beta..sub.3 and .alpha..sub.v.beta..sub.5 integrins, their
Human requiem
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This invention relates, in part, to newly identified polynucleotides and polypeptides; variants and derivatives of the polynucleotides and polypeptides; processes for making the polynucleotides and the polypeptides, and their variants and derivatives; agonists and antagonists of the polypeptides;
Human requiem
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This invention relates, in part, to newly identified polynucleotides and polypeptides; variants and derivatives of the polynucleotides and polypeptides; processes for making the polynucleotides and the polypeptides, and their variants and derivatives; agonists and antagonists of the polypeptides;
Interleukin-1 beta converting enzyme like apoptotic protease-6
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FIELD OF INVENTION
This invention relates, in part, to newly identified polynucleotides and polypeptides; variants and derivatives of the polynucleotides and polypeptides; processes for making the polynucleotides and the polypeptides, and their variants and derivatives; agonists and antagonists of
Interleukin-1.beta. converting enzyme like apoptotic protease-6
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FIELD OF INVENTION
This invention relates, in part, to newly identified polynucleotides and polypeptides; variants and derivatives of the polynucleotides and polypeptides; processes for making the polynucleotides and the polypeptides, and their variants and derivatives; agonists and antagonists of
Interleukin-1.beta. converting enzyme like apoptotic protease-6
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FIELD OF INVENTION
This invention relates, in part, to newly identified polynucleotides and polypeptides; variants and derivatives of the polynucleotides and polypeptides; processes for making the polynucleotides and the polypeptides, and their variants and derivatives; agonists and antagonists of
Interleukin-1 beta converting enzyme like apoptotic protease-7
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BACKGROUND OF THE INVENTION
Apoptosis, or programmed cell death (PCD), is a genetically regulated mechanism with a central role in both metazoan development and homeostasis. (Raff, 1992; Steller, 1995). The cell death machinery is conserved throughout evolution (Vaux et al., 1994) and is composed of
Interleukin-1 .beta. converting enzyme like apoptotic protease-6
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FIELD OF INVENTION
This invention relates, in part, to newly identified polynucleotides and polypeptides; variants and derivatives of the polynucleotides and polypeptides; processes for making the polynucleotides and the polypeptides, and their variants and derivatives; agonists and antagonists of
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