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9 resultados
Methods for increasing the stabilization of hypoxia inducible factor-.alpha.
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FIELD OF THE DISCLOSURE
Disclosed herein are prolyl hydroxylase inhibitors that can stabilize hypoxia inducible factor-1 alpha (HIF-1.alpha.), as well as hypoxia inducible factor-2 alpha (HIF-2.alpha.). Also disclosed herein are pharmaceutical compositions comprising one or more of the disclosed
Methods for increasing the stabilization of hypoxia inducible factor-1 alpha
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FIELD OF THE DISCLOSURE
Disclosed herein are prolyl hydroxylase inhibitors that can stabilize hypoxia inducible factor-1 alpha (HIF-1.alpha.), as well as hypoxia inducible factor-2 alpha (HIF-2.alpha.). Also disclosed herein are pharmaceutical compositions comprising one or more of the disclosed
Methods for increasing the stabilization of hypoxia inducible factor-1 alpha
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FIELD OF THE DISCLOSURE
Disclosed herein are prolyl hydroxylase inhibitors that can stabilize hypoxia inducible factor-1 alpha (HIF-1.alpha.), as well as hypoxia inducible factor-2 alpha (HIF-2.alpha.). Also disclosed herein are pharmaceutical compositions comprising one or more of the disclosed
Methods for increasing the stabilization of hypoxia inducible factor-1 alpha
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FIELD OF THE DISCLOSURE
Disclosed herein are prolyl hydroxylase inhibitors that can stabilize hypoxia inducible factor-1 alpha (HIF-1.alpha.), as well as hypoxia inducible factor-2 alpha (HIF-2.alpha.). Also disclosed herein are pharmaceutical compositions comprising one or more of the disclosed
Enhanced erythropoiesis and iron metabolism
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FIELD OF THE INVENTION
The present invention relates to methods and compounds for regulating or enhancing erythropoiesis and iron metabolism, and for treating or preventing iron deficiency and anemia of chronic disease.
BACKGROUND OF THE INVENTION
Anemia generally refers to any abnormality in
Pharmaceutical compounds, preparation, use and intermediates therefor and their preparation
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This invention relates to ethers useful in medicine, to the preparation of such compounds, to pharmaceutical formulations containing such compounds and the preparation of such formulations, to the use of the compounds in medicine, and to novel intermediates for the said compounds and the preparation
Method of extending the vascular dwell-time of particulate therapeutic and particulate diagnostic agents
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TABLE OF CONTENTS
1. Technical Field
2. Background of the Invention
3. Summary of the Invention
4. Detailed Description of the Invention
4.1 The Mode of the Invention
4.2 Mode of Administration
5. Examples
5.1 Biological Data
1. TECHNICAL FIELD
The present invention relates to a method for
Method of extending the vascular dwell-time of particulate therapeutic and particulate diagnostic agents
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1. TECHNICAL FIELD
The present invention relates to a method for increasing the vascular dwell-time of a particulate therapeutic or particulate diagnostic agent in a mammal through the adjunct administration of an effective amount of the particulate therapeutic or particulate diagnostic agent and an
Pharmaceutical ethers
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This invention relates to ethers useful in medicine, to the preparation of such compounds, to pharmaceutical formulations containing such compounds and the preparation of such formulations, to the use of the compounds in medicine, and to novel intermediates for the said compounds and the preparation
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