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12 resultados
The Effect of Acute Minocycline Administration on Emotional Processing and Cognition in Healthy Volunteers
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Current antidepressant treatments, which largely target monoamine pathways, are efficacious in treating many aspects of major depression, however it is estimated that more than 30% of depressed patients fail to respond to standard antidepressant medications. Thus, there is a strong clinical need to
Evaluation of Schemes of Administration of Intravenous Ketamine in Depression
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1. Background 1.1 Major depressive disorder (MDD) MDD is a clinical syndrome characterized by the presence of low modo, anhedonia, appetite and weight changes, sleep disturbances, psychomotor alterations, fatigue, guilt and low self-esteem, ideas related to death or suicide, and concentration
Mobile Virtual Positive Experiences for Anhedonia
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Anhedonia is a symptoms dimension that characterizes many individuals suffering from depression, as well as some types of anxiety, psychosis, and substance use. Anhedonia refers to deficits in positive affect as observed through 1) loss of enjoyment in pleasurable activities and/or 2) loss of desire
A Neurosteroid Intervention for Menopausal and Perimenopausal Depression
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Despite the introduction of new antidepressants, major depressive disorder (MDD) remains challenging to treat. Antidepressant effectiveness trials conducted suggest depression remission rates of only 15%-35%. Therefore, new antidepressants with mechanisms that move beyond norepinephrine and
PET-MRI F-DOPA Activity in the Mesocorticolimbic System and Depressive Symptoms in the Prediction of Treatment Compatibility
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Introduction:
Major depressive disorder (MDD) is a versatile psychiatric disorder with a prevalence of 8-12 % of the population in many countries.
According to current approach MDD is characterized by lowered activity of monoamine neurotransmitters, it is undetermined whether it is as a result of
Depressed Mood Improvement Through Nicotine Dosing (Depressed MIND Study)
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Late-life depression (LLD) is characterized both by affective symptoms and cognitive deficits. The co-occurrence of cognitive deficits in LLD is a clinically relevant phenotype characterized by significant disability and poor antidepressant response. Cognitive deficits can persist even with
Links Between Depression, Anxiety, Coping and Quality of Life After a Stroke
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Introduction and literature review With 130 000 cases per year in France in 2010, stroke is one of the most common neurological diseases, often leaving many disabling sequelae physical and cognitive levels (currently live 500 000 disabled following a stroke) and leading and a loss of significant
Investigating the Effects of Typhoid Vaccine on Sleep in Healthy Volunteers
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Elevated levels of pro-inflammatory cytokines are implicated in the pathogenesis of major depression. Both clinical and animal studies have shown that pro-inflammatory cytokines can induce a behavioural repertoire of symptoms collectively referred to as 'sickness behaviours,' which include cognitive
Music Therapy in the Treatment of Chronic Obstructive Pulmonary Disease
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This study examines the effect of a multimodal psycho-music therapy intervention on respiratory symptoms (dyspnea), depression, and quality of life of patients with pulmonary disease during Pumonary Rehabilitation, in the combined effort of two departments of Mount Sinai Beth Israel: The Alice
Study of Ruxolitinib in the Treatment of Cachexia in Patients With Tumor-Associated Chronic Wasting Diseases.
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Cachexia is a multifactorial syndrome characterized by tissue wasting, loss of body weight, particularly of lean body (muscle) mass (LBM) and to a lesser extent adipose tissue, metabolic alterations, fatigue, reduced performance status, and very often accompanied by anorexia leading to a reduced
Pilot Study to Evaluate Individualized Choice of Antidepressants in Patients With Cancer
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Major depressive disorder (MDD) is a debilitating illness associated with increased mortality and significant impairment in quality of life. The prevalence of MDD is particularly high in patients with cancer, as much as 38% in some studies.
The study of depression in cancer patients is particularly
Dopamine Receptor Imaging in Mood Disorders
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The dopaminergic projections from the substantia nigra and the ventral tegmental area into the ventral striatum and medial prefrontal cortex (mPFC) play major roles in the neural processing underlying motivated behavior. Hypofunction of this system is hypothesized to underlie the anhedonia,
La base de datos de hierbas medicinales más completa respaldada por la ciencia
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* Toda la información se basa en investigaciones científicas publicadas.
