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aquilaria/antineoplásico

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ArtículosEnsayos clínicosPatentes
13 resultados

Plant anticancer agents. XIX Constituents of Aquilaria malaccensis.

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The stem bark of the Thai tree Aquilaria malaccensis (Thymelaeaceae) has afforded 1,3-dibehenyl-2-ferulyl glyceride (3), which is novel, and 12-O-n-deca- 2, 4, 6-trienoylphorbol-13-acetate (4). The structures of these cytotoxic compounds were elucidated by their spectral and chemical parameters.

Phenylethylchromones with In Vitro Antitumor Promoting Activity from Aquilaria filaria.

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A new chromone, 2-(2-hydroxy-2-phenylethyl)chromone (1), was isolated together with ten known phenylethyl chromones from MeOH extracts of agarwood (Aquilaria filaria). The selected compounds were evaluated in an antiproliferative assay against five human tumor cell lines, including a

Antitumor and antimicrobial activities of endophytic fungi from medicinal parts of Aquilaria sinensis.

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The purpose of this study was to isolate and characterize endophytic fungi from the stem tissue which can produce fragrant ingredients in Aquilaria sinensis (also called agarwood) to determine their antitumor and antimicrobial activities. Twenty-eight fungal endophytes were isolated from agarwood by

[Study on volatile components from peel of Aquilaria sinensis and the anti-tumor activity].

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OBJECTIVE To study the volatile constituents from peel of Aquilaria sinensis (Lour.) Gilg. and its anti-tumor activity. METHODS The volatile components from peel of A. sinensis were extracted by chloroform and analysed by the GC-MS technique. Assay the peel extract of A. sinensis on MCF-7 cell

[Chemical constituents of endophytic fungus Nodulisporium sp. A4 from Aquilaria sinensis].

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OBJECTIVE To investigate the chemical constituents of an endophytic fungus, Nodulisporium sp. A4, from the medicinal plant Aquilaria sinensis and search for antitumor natural products. METHODS The fungus was cultured in liquid medium and extracted with EtOAc. The compounds were isolated by various

In vivo toxicity and antitumor activity of essential oils extract from agarwood (Aquilaria crassna).

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BACKGROUND Aquilaria crassna has been used in traditional Asian medicine to treat vomiting, rheumatism, asthma, and cough. Furthermore, earlier studies from our laboratory have revealed that the essential oil extract from agarwood inhibited colorectal carcinoma cells. Despite of the wide range of

Identification of cucurbitacins and assembly of a draft genome for Aquilaria agallocha.

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BACKGROUND Agarwood is derived from Aquilaria trees, the trade of which has come under strict control with a listing in Appendix II of the Convention on International Trade in Endangered Species of Wild Fauna and Flora. Many secondary metabolites of agarwood are known to have medicinal value to
The present study reports a bioassay-guided isolation of β-caryophyllene from the essential oil of Aquilaria crassna. The structure of β-caryophyllene was confirmed using FT-IR, NMR and MS. The antimicrobial effect of β-caryophyllene was examined using human pathogenic bacterial and fungal strains.

Aquilaria spp. (agarwood) as source of health beneficial compounds: A review of traditional use, phytochemistry and pharmacology.

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BACKGROUND Aquilaria spp. (agarwood) has been a part of Ayurvedic and Traditional Chinese Medicine for centuries. Agarwood has also been used as a traditional medicine in Southeast Asian countries, Bangladesh and Tibet. Its common uses include the treatment of joint pain, inflammatory-related

Ameliorative Effects of Aquilaria malaccensis Leaves Aqueous Extract on Reproductive Toxicity Induced by Cyclophosphamide in Male Rats.

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Background
Cyclophosphamide (CP) is a widely used anti-neoplastic and immunosuppressive agent that is associated with adverse side effects including reproductive toxicity. Aquilaria malaccensis (AM) is a traditional medicinal plant which was reported to exhibit high

Screening of anticancer activity from agarwood essential oil.

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BACKGROUND Agarwood is a priceless non-timber forest product from Aquilaria species belonging to the Thymelaeaceae family. As a result of a defence mechanism to fend off pathogens, Aquilaria species develop agarwood or resin which can be used for incense, perfumery, and traditional medicines.

New 2-(2-phenylethyl)chromone derivatives from agarwood and their inhibitory effects on tumor cells.

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Two new chromone derivatives, 7-hydroxy-2-[2-(3'-methoxy-4'-hydroxyphenyl)-ethyl]chromone (1), and 6,7-dimethoxy-2-[2-(3'-hydroxyphenyl)-ethyl]chromone (2) were isolated from the EtOH extract of agarwood of Aquilaria sinensis, together with eleven known analogues. Their structures were established

Ethnopharmacological Survey of Herbal Remedies Used for the Treatment of Cancer in the Greater Casablanca-Morocco.

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Medicinal plants played an important role in traditional medicine for the treatment of diseases since antiquities. The aim of the study is to carry out an ethnobotanical survey on medicinal plants used traditionally in cancer treatment in the region of Greater Casablanca-Morocco, and to enhance the
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