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benzoylecgonine/infartarse
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8 resultados
[Cerebral hemorrhages and infarcts following use of cocaine].
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With increasing abuse of cocaine and purity of this drug, the incidence of strokes in relatively young people is also increasing. We describe two patients, one 29 years, the other one 33 years old. Both were well-known cocaine users. The first patient presented with an intracranial haemorrhage; the
Effect of recent cocaine use on the specificity of cardiac markers for diagnosis of acute myocardial infarction.
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We evaluated whether recent cocaine use alters the specificity of CK-MB, myoglobin, and cardiac troponin I for acute myocardial infarction (AMI) in patients who are seen in the emergency department for chest pain. Patients <60 years old with potential myocardial ischemia underwent a standardized
Thoracic aortic dissection associated with cocaine abuse.
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Cardiovascular complications of cocaine abuse include myocardial ischemia and infarction, dysrhythmias, cardiomyopathies and aortic dissection. The case in point pertains to a 26-year-old, Caucasian male, substance abuser who suffered a thoracic aortic dissection following the use of crack cocaine.
Effects of cocaine on human platelet aggregation in vitro.
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BACKGROUND
A temporal relationship has been established between cocaine ingestion and myocardial infarction, and a cocaine-induced increase in platelet aggregation has been suggested as a possible explanation. However, the mechanisms of cocaine associated coronary thrombosis have yet to be
Cocaine in sudden and unexpected death: a review of 49 post-mortem cases.
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Cocaine is a potent sympathomimetic drug that is associated with cardiotoxicity, including ventricular arrhythmia, systemic hypertension, acute myocardial infarction and left ventricular hypertrophy. The use of cocaine in Australia has risen steadily since the late 1990s. What remains unclear in the
Fetal and newborn death associated with maternal cocaine use.
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Data collected from 25 cases of fetal or newborn death associated with maternal cocaine use are reported. The average week of gestation at which fetal death occurred was week 30. Abruptio placentae was observed in 7 cases and placental infarct was found in 4 cases. The average fetal blood cocaine
Concurrent use of cocaine and alcohol by patients treated in the emergency department.
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OBJECTIVE
To compare the demographics, presenting signs and symptoms, morbidity, and mortality of emergency department patients with drug screen results positive for benzoylecgonine ester (BE; a cocaine metabolite) and those positive for BE and alcohol.
METHODS
We carried out a retrospective cohort
Cocaine and specific cocaine metabolites induce von Willebrand factor release from endothelial cells in a tissue-specific manner.
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OBJECTIVE
Cocaine use is associated with arterial thrombosis, including myocardial infarction and stroke. Cocaine use results in increased plasma von Willebrand factor (VWF), accelerated atherosclerosis, and platelet-rich arterial thrombi, suggesting that cocaine activates the endothelium, promoting
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