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benzoylecgonine/inflamación

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Interference by nonsteroidal anti-inflammatory drugs in EMIT and TDx assays for drugs of abuse.

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Fourteen nonsteroidal anti-inflammatory drugs were evaluated for interference in EMIT and TDx assays for drugs of abuse. Only tolmetin demonstrated significant interferences in the EMIT assay. Urine samples that contained high concentrations of tolmetin (1800 mg/L) had characteristic high molar
A multiclass wide-scope screening of organic contaminants in natural and waste water has been developed and validated for qualitative purposes, i.e. detection and reliable identification of compounds detected in samples at a certain level of concentration. The screening is based on the use of liquid

Illicit drugs and pharmaceuticals in swimming pool waters.

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The occurrence of illicit drugs (cocaine, opioids, amphetamines and cannabis derivatives), some of their metabolites and 48 pharmaceuticals, was investigated in pool and source waters in ten Italian indoor swimming pools. The samples were analyzed by highperformance liquid chromatography-tandem mass

Determination of the dermal penetration of esterom components using microdialysis sampling.

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OBJECTIVE Esterom Solution, an investigational pharmaceutical product, is derived from the esterification of benzoylmethylecgonine (cocaine) in 1.2 propanediol. The resulting solution contains a mixture of components. Esterom Solution is intended to be a topical analgesic to relieve pain and

Immunosuppression and oxidative stress induced by acute and chronic exposure to cocaine in rat.

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The objective of the present study was to verify if immunosuppression caused by cocaine (CO) can be mediated, at least in part, by increased formation of oxidative metabolites and reactive oxygen species (ROS) in rat. Pharmacokinetics of cocaine and its metabolites, cell-mediated immune function and
The main aim of the presented research is to introduce a new technique, ultra performance liquid chromatography-positive/negative electrospray tandem mass spectrometry (UPLC-ESI/MS/MS), for the development of new simultaneous multiresidue methods (over 50 compounds). These methods were used for the

Removal of emerging contaminants in sewage water subjected to advanced oxidation with ozone.

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Advanced oxidation processes (AOP) based on ozone treatments, assisted by ultrasounds, have been investigated at a pilot-plant scale in order to evaluate the removal of emerging contaminants in sewage water. Around 60 emerging contaminants, mainly pharmaceuticals from different therapeutically

The occurrence of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs in surface water in South Wales, UK.

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The presence and fate of 56 pharmaceuticals, personal care products, endocrine disruptors and illicit drugs (PPCPs) were investigated in the South Wales region of the UK. Two contrasting rivers: River Taff and River Ely were chosen for this investigation and were monitored for a period of 10 months.
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