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d alpha tocopherol/atrofia
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Intensive anti-oxidant pretreatment retards motor nerve degeneration.
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Intensive pretreatment of cats with a combination of the antioxidants D-alpha-tocopherol (200 IU) and selenium (50 micrograms) once daily for 5 days (p.o.) was found to significantly preserve the functional capacity of degenerating soleus motor nerve terminals (measured at 48 h after axon section at
Role of lipid peroxidation in post-traumatic spinal cord degeneration: a review.
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A large amount of biochemical, physiological, and pharmacological data has been obtained which supports a mechanistic role of oxygen free radical-induced lipid peroxidation (LP) in post-traumatic spinal cord degeneration. Biochemical evidence of early and progressive lipid peroxidative reactions
Glucose alters the susceptibility of mesangial cells to contrast media.
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OBJECTIVE
Diabetic patients frequently suffer contrast media-induced nephropathy. Hyperglycemia in diabetes mellitus causes gradual deterioration of glomerular mesangial cells (MCs) in the kidney. In this study, the authors investigated the response of rat MCs cultured in high-glucose medium to
Excretion of alpha-tocopherol into human seminal plasma after oral administration.
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In this open controlled study, we investigated the blood and seminal plasma concentrations of alpha-tocopherol in 15 unselected male volunteers, who received either 600, 800 or 1200 mg d-alpha-tocopherol per day for 3 weeks. During the intervention, both the blood and seminal plasma vitamin E
Potential Protective Effects of Naringin on Oculo-Pulmonary Injury Induced by PM 10 (Wood Smoke) Exposure by Modulation of Oxidative Damage and Acetylcholine Esterase Activity in a Rat Model
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Background: Millions of households in the world depend on wood and biomass for cooking and heating. This dependence leads to undesirable toxic effects, such as ocular and pulmonary toxicity.
Objectives: The present study examined
Role of reactive oxygen species in protein degradation in murine myotubes induced by proteolysis-inducing factor and angiotensin II.
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The antioxidants butylated hydroxytoluene (BHT, 1 mM) and D-alpha-tocopherol (10 microM) completely attenuated protein degradation in murine myotubes in response to both proteolysis-inducing factor (PIF) and angiotensin II (Ang II), suggesting that the formation of reactive oxygen species (ROS)
Improving Tumor Hypoxia and Radiotherapy Resistance via in situ Nitric Oxide Release Strategy.
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Radiation therapy remains one of the main treatments for cancer. However, conventional radiotherapy not only manifests a low radiation accumulation in the tumor site, but also displays numerous negative effects. The most serious clinical problem is the radiotherapy resistance leading to cancer
Modulation of inflammation by vitamin E and C supplementation prior to anterior cruciate ligament surgery.
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Muscle atrophy commonly follows anterior cruciate ligament (ACL) injury and surgery. Proinflammatory cytokines can induce and exacerbate oxidative stress, potentiating muscle atrophy. The purpose of this study was to evaluate the influence of prior antioxidant (AO) supplementation on circulating
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