4 resultados
(-)-Cathinone and d-norpseudoephedrine (DNE) in the dose range 0.2-1.2 mg/ml produced a reduction in contractions of skeletal muscle, evoked by direct and indirect electrical stimulation and antagonised the facilitatory action of physostigmine on the neuromuscular junction; but failed to antagonise
d-Norpseudoephedrine, a central stimulant present in Catha edulis, is excreted unchanged in human urine. The alkaloid was detected in urine 30-50 min after ingestion of synthetic d-norpseudoephedrine, and trace amounts of the drug could still be detected 24 hr later. Approximately 40% of ingested
The effect of khat (Catha edulis Forsk., family Celastraceae), a plant used for its stimulant effects in eastern Africa and southern Arabia, has until recently been attributed to the pharmacological action of d-norpseudoephedrine, also known as cathine. The isolation in 1975 of cathinone revived an