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7 resultados
Isolated farnesyl protein transferase enzyme
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to the identification and characterization of an enzyme involved in expression of the cancer phenotype, as well as to the identification and selection of compounds for its inhibition. In particular aspects, the invention
Methods and compositions for inhibiting farnesyl transferase enzyme
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to the identification and characterization of an enzyme involved in expression of the cancer phenotype, as well as to the identification and selection of compounds for its inhibition. In particular aspects, the invention
Method for identifying farnesyl transferase inhibitors
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to the identification and characterization of an enzyme involved in expression of the cancer phenotype, as well as to the identification and selection of compounds for its inhibition. In particular aspects, the invention
Methods of assaying farnesyl transferase
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to the identification and characterization of an enzyme involved in expression of the cancer phenotype, as well as to the identification and selection of compounds for its inhibition. In particular aspects, the invention
Method of inhibiting a farnesyl transferase enzyme
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to the identification and characterization of an enzyme involved in expression of the cancer phenotype, as well as to the identification and selection of compounds for its inhibition. In particular aspects, the invention
Tetrapeptide-based inhibitors of farnesyl transferase
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to the molecular cloning, purification, characterization and inhibition of farnesyl:protein transferase, an enzyme involved in expression of the cancer phenotype, for example, in the transfer of farnesyl groups to oncogenic
Methods and compositions for the identification, characterization, and inhibition of farnesyl protein transferase
Solo los usuarios registrados pueden traducir artículos
Iniciar sesión Registrarse
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to the molecular cloning, purification, characterization and inhibition of farnesyl:protein transferase, an enzyme involved in expression of the cancer phenotype, for example, in the transfer of farnesyl groups to oncogenic
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